Results 51 to 60 of about 3,147,351 (292)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A Fuzzy Control Strategy for Multi-Goal Autonomous Robot Navigation

Sensors
This paper addresses the complex problem of multi-goal robot navigation, framed as an NP-hard traveling salesman problem (TSP), in environments with both static and dynamic obstacles. The proposed approach integrates a novel path planning algorithm based
Stavros Stavrinidis, Paraskevi Zacharia, Elias Xidias   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Strategic insight and age-related goal neglect influence risky decision-making

Frontiers in Neuroscience, 2012
Maximizing long-run gains often requires taking on some degree of risk, yet decision-makers often exhibit risk aversion (RA), rejecting risky prospects even when these have higher expected value than safer alternatives.
Andrew eWestbrook, Bruna eMartins, Tal eYarkoni, Todd S Braver   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

System of Balanced Scorecard and its Impelementation in Management of Norwegian Air Force and other Military Organizations [PDF]

INCAS Bulletin, 2012
The system of Balanced Scorecard is one of the most successful modern tools of strategic management at present. Being a strategic, management and planning system, the main aim of the BSC is to help the top management of companies, firms, corporations and
Pavel NEČAS, Radoslav IVANČÍK
doaj   +1 more source

MIMAC : A micro-tpc matrix for directional detection of dark matter

, 2010
Directional detection of non-baryonic Dark Matter is a promising search strategy for discriminating WIMP events from background. However, this strategy requires both a precise measurement of the energy down to a few keV and 3D reconstruction of tracks ...
A Delbart, Ahlen S, Aprile E, C Golabek, C Grignon, Ch Fourel, D Santos, E Ferrer, F J Iguaz, F Mayet, G Bosson, Grignon C, I Giomataris, J Billard, J L Bouly, J P Mols, J P Richer, L Lebreton, Moulin E, O Bourrion, O Guillaudin, Santos D, Santos D   +22 more
core   +8 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Q-Strategy: A Bidding Strategy for Market-Based Allocation of Grid Services [PDF]

, 2008
The application of autonomous agents by the provisioning and usage of computational services is an attractive research field. Various methods and technologies in the area of artificial intelligence, statistics and economics are playing together to ...
A. Sherstov, C. Watkins, D. Cliff, D. Gode, D. Minoli, E. Medernach, H.J. Herik van den, I. Erev, K. Lai, L. Panait, M. He, M. Wellman, P. Green, R. Luce, R. Wolski, S. Gjerstad, S. Kaplan, T. Saaty, W. Smith, Y. Shoham   +19 more
core   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source