Results 61 to 70 of about 3,147,351 (292)
Do humans optimally exploit redundancy to control step variability in walking? [PDF]
PLoS Computational Biology, 2010 It is widely accepted that humans and animals minimize energetic cost while walking. While such principles predict average behavior, they do not explain the variability observed in walking.
Jonathan B Dingwell +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Robust semantic analysis for adaptive speech interfaces [PDF]
, 2003 The DUMAS project develops speech-based applications that are adaptable to different users and domains. The paper describes the project's robust semantic analysis strategy, used both in the generic framework for the development of multilingual speech ...
Cheadle, Maria, Gambäck, Björn
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Complexity, strategic thinking and organisational change [PDF]
, 2003 Comparative considerations of strategy from complexity paradigm and Newtonian paradigm perspectives are discussed in the light of three ideological dispositions towards the future. We term them defensive, opportunist, and goal oriented.
Carlisle, Ysanne, McMillan, Elizabeth
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
INTEGRATION ANALYSIS OF THE ENTERPRISE'S EXTERNAL ENVIRONMENT AND INTERNAL CAPACITY
Вестник Северо-Кавказского федерального университета, 2022 The article sets as the goal on the basis of the integration analysis of the external environment and the internal capacity of the enterprise to develop a number of targets that can serve as the basis for the formation and subsequent implementation of ...
E. Depershmidt
doaj
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
EIRP Proceedings, 2009 Sustainable development has become a political objective of the European Unionsince 1997 through its inclusion in the Maastricht Treaty. In 2001, the Gothenburg EuropeanCouncil adopted the Sustainable Development Strategy of the European Union, which had
Domnica Doina Parcalabu, Georgeta Modiga
doaj