Results 61 to 70 of about 1,298,870 (397)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Chemical Quality of Longissimus Muscles of Kacang Goat After Supplemented With A Combination of Palm Kernel Meal and Powdered Katuk Leaf [PDF]

open access: yesE3S Web of Conferences, 2020
The purpose of this study was to analyze the effect of supplementation of palm kernel meal (BIS), Katuk leaf powder (KAT), and their combination on the chemical quality of Longissimus dorsi muscle in Kacang goats. Twenty male Kacang goats aged +1.5 years
Razali Razali   +7 more
doaj   +1 more source

Development of breeding schemes in overseas regions: the case of goats for meat production in the Reunion Island [PDF]

open access: yes, 2012
In the French island of Reunion, (Indian Ocean, 800,000 inhabitants), 37,600 goats are reared mainly for meat production. Farming systems are very diverse but they still constitute a secondary activity generating an income supplement.
Fontaine, Olivia
core  

Genealogical data of Boer and Nubian goats in Mexico [PDF]

open access: yes, 2020
The pedigree file of the Boer and Nubian goat breeds in Mexico was constructed using the national database provided by the Asociación Mexicana de Criadores de Ganado Caprino de Registro.
Ben Zaabza, H.   +5 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

PENGARUH PERBANDINGAN PEMANIS (SUKROSA, FRUKTOSA DANGLUKOSA) TERHADAP KUALITAS PERMEN SUSU KAMBING PERANAKAN ETAWA (PE) SECARA FERMENTASI [PDF]

open access: yes, 2009
Milk is the valuable and perfect food-stuff of high nutrition, because containing most of food subtance like carbohydrate, protein, fat, vitamin and mineral.
Pramesti Wijaya, Vera
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Immunoglobulin G content and colostrum composition of different goat and sheep breeds in Switzerland and Germany.

open access: yesJournal of Dairy Science, 2019
Colostrum represents the sole source to acquire humoral immunity and is an important energy source for newborn lambs and goat kids. However, colostrum composition (i.e., the contents of IgG, fat, protein, and lactose) is affected by various factors such ...
E. Kessler, R. Bruckmaier, J. Gross
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Determining Appropriate Numbers and Times of Daily Measurements Using GreenFeed System to Estimate Ruminal Methane Emission of Meat Goats

open access: yesAnimals
The study was conducted to determine appropriate numbers and times of daily gas measurements to estimate total daily methane (CH4) emission of meat goats using a GreenFeed system (GFS). A replicated 4 (four measurement protocols) × 4 (four periods) Latin
Dereje Tadesse   +6 more
doaj   +1 more source

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