Development of duplex PCR for differential detection of goatpox and sheeppox viruses [PDF]
Background Clinically, sheeppox and goatpox have the same symptoms and cannot be distinguished serologically. A cheaper and easy method for differential diagnosis is important in control of this disease in endemic region.
Zhixun Zhao +7 more
doaj +3 more sources
Epidemiological Study and Molecular Characterization of Lumpy Skin Disease in Cattle in Egypt. [PDF]
Lumpy skin disease virus (LSDV) constitutes one of the most significant poxvirus infections impacting livestock and has a high morbidity rate and a comparatively low mortality rate. This study was designed to elucidate the epidemiology and the molecular analysis of LSDV using conventional polymerase chain reaction (PCR) to amplify the extracellular ...
El-Nady HH +8 more
europepmc +2 more sources
Phylogenetic analysis of Chinese sheeppox and goatpox virus isolates [PDF]
Background Sheeppox virus (SPPV) and goatpox virus (GTPV), members of the Capripoxvirus genus of the Poxviridae family are causative agents of sheep pox and goat pox respectively, which are important contagious diseases and endemic in central and ...
Zhou Tao +9 more
doaj +3 more sources
Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus [PDF]
Lumpy skin disease, goatpox, and sheeppox have rapidly spread in many countries, leading to the emergence of new mutant strains that have caused substantial damage and posed significant threats to animal husbandry in endemic areas. Effective surveillance
Wanying Wang +12 more
doaj +2 more sources
Development of a potential vaccine against Capripox virus implementing reverse vaccinology and pan-genomic immunoinformatics. [PDF]
CPXV is responsible for animal diseases affecting cattle (Lumpy Skin Disease), sheep (Sheeppox), and goats (Goatpox). During outbreaks, these diseases have huge socio-economic effects.
Md Mohaimenul Islam Tareq +9 more
doaj +2 more sources
Exploring the function and pathogenicity of Goatpox virus N1L gene using recombinant vaccinia virus Tiantan strain [PDF]
The N1L gene is a well-characterized virulence factor in the poxvirus family; however, its functional role in Goatpox virus (GTPV) remains poorly understood.
Jialiang Xin +12 more
doaj +2 more sources
Which Proteins? The Challenge of Identifying the Protective Antigens for Next-Generation Capripoxvirus Vaccines [PDF]
Sheeppox, goatpox, and lumpy skin disease continue to negatively impact the sheep, goat, and cattle industries in countries where these diseases are present and threaten to spread into new regions. Effective vaccines are available for disease control and
Mahder Teffera +3 more
doaj +2 more sources
A GTPV-Based Murine Model Recapitulating Key Features of Lumpy Skin Disease for Preclinical Vaccine Evaluation [PDF]
The global spread of lumpy skin disease (LSD), a devastating cattle disease caused by the lumpy skin disease virus (LSDV), is hampered by the lack of a practical small animal model for vaccine evaluation. Here, we established a mouse model by challenging
Wanfeng Ji +7 more
doaj +2 more sources
Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update [PDF]
Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across Asia and Europe in recent years. The LSD virus (LSDV) is a relatively poorly studied virus.
Naveen Kumar +2 more
doaj +2 more sources
RNA interference targeting virion core protein ORF095 inhibits Goatpox virus replication in Vero cells [PDF]
Background Goatpox is an economically important disease in goat and sheep-producing areas of the world. Many vaccine strategies developed to control the disease are not yet completely successful.
Zhao Zhixun +8 more
doaj +3 more sources

