Results 21 to 30 of about 1,347 (135)

Development of a multiplex real-time PCR for the simultaneous detection of monkeypox virus clades I, II, and goatpox virus [PDF]

Frontiers in Veterinary Science
IntroductionMonkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health.
Zhidong Zhang, Yongqiang Lin
exaly   +4 more sources

A Genome-Wide Screening of Novel Immunogenic TrLSDV103 Protein of Lumpy Skin Disease Virus and Its Application for DIVA. [PDF]

FASEB J
Using the VirScan platform covering 4522 LSDV protein sequences, sera from 20 LSDV‐infected and 20 GTPV‐vaccinated cattle were used to screen phage libraries. Sequencing and bioinformatics analyses revealed peptides covering the TrLSDV103 protein. The candidate antigen was subsequently expressed, confirmed for its DIVA capability, and used to develop ...
Yuan X, Dong J, Xiang Z, Zhang Q, Tao P, Guo A.   +5 more
europepmc   +2 more sources

Does Lumpy Skin Disease Have the Potential to Become Zoonotic? [PDF]

J Med Virol
Journal of Medical Virology, Volume 97, Issue 8, August 2025.
Velazquez-Salinas L, Harvey AM, Mire C.
europepmc   +2 more sources

Phylogenetic Analysis, Morphological Characteristics, and Cellular Tropism of Vaccine-Like Recombinant Strains of Lumpy Skin Disease Virus in China. [PDF]

Transbound Emerg Dis
Lumpy skin disease virus (LSDV) causes lumpy skin disease (LSD), a highly contagious cattle disease that leads to substantial economic losses to the global cattle industry. Currently, it is imperative to further elucidate its biological characteristics and analyze the global epidemiological dynamics.
Gong Z, Li J, Zou Y, Dai J, Liu S, Li L, Feng C, Sun F, Li X, Liu C, Wang Z, Liu G, Yang Z.   +12 more
europepmc   +2 more sources

A GTPV-Based Murine Model Recapitulating Key Features of Lumpy Skin Disease for Preclinical Vaccine Evaluation [PDF]

Animals
The global spread of lumpy skin disease (LSD), a devastating cattle disease caused by the lumpy skin disease virus (LSDV), is hampered by the lack of a practical small animal model for vaccine evaluation. Here, we established a mouse model by challenging
Wanfeng Ji, Xinjun Zhou, Sen Zhang, Xinwei Yuan, Wenying Wu, Xiaowen Xu, Aizhen Guo, Yingyu Chen   +7 more
doaj   +2 more sources

Development of a potential vaccine against Capripox virus implementing reverse vaccinology and pan-genomic immunoinformatics. [PDF]

PLoS ONE
CPXV is responsible for animal diseases affecting cattle (Lumpy Skin Disease), sheep (Sheeppox), and goats (Goatpox). During outbreaks, these diseases have huge socio-economic effects.
Md Mohaimenul Islam Tareq, Sattyajit Biswas, Farazi Abinash Rahman, Labib Sharirar Siam, Sadia Jannat Tauhida, Shamim Ahmed, Hasan Jafre Shovon, Mariya Ahmed, Kazi Afrin Jerin, Md Nazmul Hasan   +9 more
doaj   +2 more sources

Epidemiological Study and Molecular Characterization of Lumpy Skin Disease in Cattle in Egypt. [PDF]

Vet Med Int
Lumpy skin disease virus (LSDV) constitutes one of the most significant poxvirus infections impacting livestock and has a high morbidity rate and a comparatively low mortality rate. This study was designed to elucidate the epidemiology and the molecular analysis of LSDV using conventional polymerase chain reaction (PCR) to amplify the extracellular ...
El-Nady HH, Mansour A, Eissa MI, Abou-Zeid NZ, Fawzi EM, El-Raof AMA, Sobeih AA, Bakrash MM, Shazly YAE.   +8 more
europepmc   +2 more sources

Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus [PDF]

Microbiology Spectrum
Lumpy skin disease, goatpox, and sheeppox have rapidly spread in many countries, leading to the emergence of new mutant strains that have caused substantial damage and posed significant threats to animal husbandry in endemic areas. Effective surveillance
Wanying Wang, Zhengwang Shi, Juncong Luo, Huancheng Liao, Lu Feng, Yuqian Zhu, Yongyu Lin, Xintai Shi, Fan Zhang, Tao Xi, Jie Chen, Hong Tian, Haixue Zheng   +12 more
doaj   +2 more sources

Development and evaluation of a multiplex PCR-based dual-platform targeted sequencing framework for precise differentiation of lumpy skin disease virus [PDF]

Frontiers in Microbiology
BackgroundLumpy skin disease virus (LSDV) shares over 96% genomic identity with goatpox and sheeppox viruses, presenting severe diagnostic challenges due to cross-reactivity.MethodsTo address this bottleneck, we established a targeted sequencing ...
Yuqi Wang, Yifei Wang, Zilong Bai, Suqiu Wang, Lin Wang, Wei Zhang, Zhiqiang Gao, Jing Pu, Sile Du, Congliang Deng, Liwei Xu, Wangxue Wu, Xiangpeng Zhao, Tong Ren, Dan Wu, Jiawei Zhang, Qiang Gu, Shaolin Wang, Xiju Shi   +18 more
doaj   +2 more sources

Molecular Characterization and Epidemiology of Lumpy Skin Disease Virus in Bhutan, 2023. [PDF]

Transbound Emerg Dis
Lumpy skin disease (LSD) is a disease of cattle and other ruminants caused by the LSD Virus (LSDV). LSD infections are characterized by high morbidity, low mortality, and significant economic impact. Initially endemic to Africa only, LSD has spread to the Middle East, Europe, and Asia in the past decade.
Sharma PM, Wangchuk P, Tshering D, La T, Rinchen S, Thapa NK, Settypalli TBK, Dundon WG, Meki IK, Lamien CE.   +9 more
europepmc   +2 more sources