RNA interference targeting virion core protein ORF095 inhibits Goatpox virus replication in Vero cells [PDF]
Background Goatpox is an economically important disease in goat and sheep-producing areas of the world. Many vaccine strategies developed to control the disease are not yet completely successful.
Zhao Zhixun +8 more
doaj +5 more sources
Development of real-time and lateral flow dipstick recombinase polymerase amplification assays for rapid detection of goatpox virus and sheeppox virus [PDF]
Background Goatpox virus (GTPV) and sheeppox virus (SPPV), which belong to the Capripoxvirus (CaPV), are economically important pathogens of small ruminants.
Yang Yang +8 more
doaj +5 more sources
Goatpox virus Hrf-063 interacts with host eIF4A1 and is associated with altered expression of antiviral signaling-related factors [PDF]
Goatpox virus (GTPV) is an important capripoxvirus that causes severe disease in goats, yet the functions of many GTPV-encoded proteins remain unclear. In this study, eukaryotic translation initiation factor 4A1 (eIF4A1) was identified as a host protein ...
Baoqin Long +32 more
doaj +3 more sources
Development of a multiplex real-time PCR for the simultaneous detection of monkeypox virus clades I, II, and goatpox virus [PDF]
IntroductionMonkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health. Clinical diagnostics continue to face challenges regarding specificity among poxviruses. The need for a rapid and precise assay
Zhidong Zhang, Yongqiang Lin
exaly +5 more sources
A GTPV-Based Murine Model Recapitulating Key Features of Lumpy Skin Disease for Preclinical Vaccine Evaluation [PDF]
The global spread of lumpy skin disease (LSD), a devastating cattle disease caused by the lumpy skin disease virus (LSDV), is hampered by the lack of a practical small animal model for vaccine evaluation. Here, we established a mouse model by challenging
Wanfeng Ji +7 more
doaj +2 more sources
Humoral and cytokine responses to a heterologous goatpox vaccine in Mithun (Bos frontalis): a longitudinal field study [PDF]
IntroductionLumpy Skin Disease (LSD), caused by a Capripoxvirus, has caused severe outbreaks among cattle in India. The disease status and vaccine response of Mithun (Bos frontalis), a semi-domesticated bovine species of major socio-economic importance ...
Gundallahalli Bayyappa Manjunatha Reddy +13 more
doaj +2 more sources
Design of a multi-epitope vaccine against goatpox virus using an immunoinformatics approach
IntroductionGoatpox, a severe infectious disease caused by goatpox virus (GTPV), leads to enormous economic losses in the livestock industry. Traditional live attenuated vaccines cause serious side effects and exist a risk of dispersal.
Qinqin Long +3 more
doaj +3 more sources
Coinfection kinetics of goatpox virus and peste-des-petits-ruminants virus in Vero cells. [PDF]
Goatpox, sheeppox, and peste-des-petits-ruminants (PPR) are economically important virus diseases affecting goats and sheep, which often cause coinfection/comorbidities in the field. Coinfection with these viruses leads to enhanced infection in natural scenarios in terms of morbidities and mortalities. Currently, individual live attenuated vaccines are
Kuniyal A +6 more
europepmc +3 more sources
Live attenuated goatpox vaccination in pregnant Murcia-Granada goats: dosage implications and outcomes [PDF]
Background Infectious diseases, particularly the Goatpox virus (GTPV) from the Poxviridae family, significantly impact livestock health and agricultural economies, especially in developing regions.
Hossein Esmaeili +4 more
doaj +2 more sources
Structural and sequence analysis of the RPO30 gene of sheeppox and goatpox viruses from India
Sheeppox and goatpox are transboundary viral diseases of sheep and goats that cause significant economic losses to small and marginal farmers worldwide, including India.
Saminathan M +1 more
exaly +3 more sources

