Results 21 to 30 of about 1,536 (163)

Molecular Determinants of Species-Specific Interactions Between Protein Kinase R and Poxvirus K3 Orthologs [PDF]

Viruses
Protein kinase R (PKR) is an antiviral protein that is involved in molecular “arms races” with viral antagonists. As a result, some PKR inhibitors, including the vaccinia virus (VACV) protein K3 and its orthologs from other poxviruses only inhibit PKRs ...
Chorong Park, Greg Brennan, Chen Peng, Chi Zhang, Jingxin Cao, Loubna Tazi, Stefan Rothenburg   +6 more
doaj   +2 more sources

Optimal immunization strategies for Saanen goats against goatpox [PDF]

BMC Veterinary Research
Background Goatpox is a highly contagious disease caused by the Capripoxvirus, primarily affecting sheep and goats. Breeds like the Saanen are particularly vulnerable, especially in enzootic areas, and face risks not only from the disease itself but also
Hossein Esmaeili, Seyed Mehdi Joghataei, Zeinab Hamidiya, Ehsan Baghal Arani, Amir pasha Shakeri, Zia Nosrat Rad, Mohammad Mahdi Safari   +6 more
doaj   +2 more sources

The Development of a Multivalent Capripoxvirus-Vectored Vaccine Candidate to Protect against Sheeppox, Goatpox, Peste des Petits Ruminants, and Rift Valley Fever [PDF]

Vaccines
Capripoxviruses are the causative agents of sheeppox, goatpox, and lumpy skin disease (LSD) in cattle, which cause economic losses to the livestock industry in Africa and Asia.
Hani Boshra, Graham A. D. Blyth, Thang Truong, Andrea Kroeker, Pravesh Kara, Arshad Mather, David Wallace, Shawn Babiuk   +7 more
doaj   +2 more sources

Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus [PDF]

Microbiology Spectrum
Lumpy skin disease, goatpox, and sheeppox have rapidly spread in many countries, leading to the emergence of new mutant strains that have caused substantial damage and posed significant threats to animal husbandry in endemic areas. Effective surveillance
Wanying Wang, Zhengwang Shi, Juncong Luo, Huancheng Liao, Lu Feng, Yuqian Zhu, Yongyu Lin, Xintai Shi, Fan Zhang, Tao Xi, Jie Chen, Hong Tian, Haixue Zheng   +12 more
doaj   +2 more sources

Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update [PDF]

Virulence
Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across Asia and Europe in recent years. The LSD virus (LSDV) is a relatively poorly studied virus.
Naveen Kumar, Shalini Sharma, Bhupendra N. Tripathi   +2 more
doaj   +2 more sources

Mixed infection of peste-des-petits ruminants and Capripox in goats in South Kivu, Democratic Republic of Congo [PDF]

Journal of Advanced Veterinary and Animal Research, 2017
Objective: We aimed at determining the prevalence and characterizing the CaPV, determining the CaPV-PPRV coinfection prevalence and providing data about phylogenetic relationship between the fusion protein of PPRV and P32 gene of CaPV.
Bwihangane Ahadi Birindwa, Gitao Chege George, Bisimwa Patrick Ntagereka, Okafor Christopher, Bebora Caroline Lilly   +4 more
doaj   +3 more sources

Outbreak of recombinant lumpy skin disease virus in yaks: high mortality and systemic pathogenesis in Qinghai-Tibet Plateau yak herds. [PDF]

Front Vet Sci
The emergence of recombinant Lumpy Skin Disease Virus (LSDV) strains in Asia has led to outbreaks marked by severe skin nodules, high transmissibility, and transboundary spread, resulting in significant economic losses to cattle industries in China and ...
Hu J, Li Y, Zhang X, Lu Y, Zeng Z, Xu M, Mou S, Nawaz S, Wang D, An T, Li X, Mo Q, Li J.   +12 more
europepmc   +3 more sources

Development of a luminex-based assay for the detection of anti-capripoxvirus and rift valley fever virus antibodies in domestic ruminants [PDF]

Virology Journal
The three members of the genus capripoxvirus (CaPV), lumpy skin disease virus (LSDV), sheeppox virus (SPPV), and goatpox virus (GTPV) have common hosts and areas of overlapping geographical distribution with Rift Valley fever virus (RVFV).
Francisco J. Berguido, Tirumala Bharani Kumar Settypalli, Curé Georges Tshilenge Mbuyi, Mame Thierno Bakhom, Petrus Jansen van Vuren, Janusz T. Pawęska, Giovanni Cattoli, Reingard Grabherr, Charles Euloge Lamien   +8 more
doaj   +2 more sources

Tetra-primer amplification refractory mutation system-polymerase chain reaction (TARMS-PCR) assay in genotyping of single nucleotide polymorphism in goatpox virus p32 gene

Indian Journal of Animal Sciences, 2020
Single nucleotide polymorphisms (SNPs) are most often associated with some pathological implications. Screening out the presence of such mutations is extremely sought to know the nature of the disease outbreak.
ADARSH MISHRA, PARIMAL ROY
doaj   +2 more sources

Development of a Multi-Locus Real-Time PCR with a High-Resolution Melting Assay to Differentiate Wild-Type, Asian Recombinant, and Vaccine Strains of Lumpy Skin Disease Virus. [PDF]

Vet Sci
Lumpy skin disease virus (LSDV) affects cattle and causes significant economic damage. The live vaccine derived from an attenuated strain is effective but is associated with mild disease and skin lesions in some vaccinated cattle.
Bhakha K, Matsui Y, Buakhao N, Wanganurakkul S, Deemagarn T, Oba M, Takemae H, Mizutani T, Misawa N, Chintapitaksakul L, Yamada K, Suwankitwat N.   +11 more
europepmc   +3 more sources