Results 11 to 20 of about 91,974 (203)

Mucus and the Goblet Cell [PDF]

open access: yesDigestive Diseases, 2013
The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between commensal bacteria and the host epithelial cells. This inner colon mucus layer is rapidly renewed and converted into the outer mucus layer by host controlled endogenous proteolytic processing.
Malin E V, Johansson, Gunnar C, Hansson
openaire   +2 more sources

Goblet Cell Carcinoids of the Appendix [PDF]

open access: yesThe Scientific World Journal, 2013
Goblet cell carcinoid (GCC) tumors are a rare subgroup of neuroendocrine tumors almost exclusively originating in the appendix. The tumor most often presents in the fifth or sixth decade with a clinical picture of appendicitis or in advanced cases an abdominal mass associated with abdominal pain.
Holt, Nanna; id_orcid 0000-0002-2032-1691   +1 more
openaire   +3 more sources

Vasoactive intestinal peptide regulates ileal goblet cell production in mice

open access: yesPhysiological Reports, 2020
Innervation of the intestinal mucosa has gained more attention with demonstrations of tuft and enteroendocrine cell innervation. However, the role(s) these fibers play in maintaining the epithelial and mucus barriers are still poorly understood.
Luke A. Schwerdtfeger, Stuart A. Tobet
doaj   +1 more source

Clinical and morphological analysis of dysplasia in Barrett's esophagus and columnar-lined esophagus

open access: yesAlʹmanah Kliničeskoj Mediciny, 2020
Background: Barrett's esophagus (BE) is a precan-cerous disease of the esophagus. The risk of adenocarcinoma in BE patients increases with the extension of segment length and with the presence of dysplasia.
L. M. Mikhaleva   +7 more
doaj   +1 more source

Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]

open access: yesPLoS ONE, 2015
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
doaj   +1 more source

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis

open access: yeseLife, 2021
Intestinal goblet cells maintain the protective epithelial barrier through mucus secretion and yet sample lumenal substances for immune processing through formation of goblet cell associated antigen passages (GAPs).
Jenny K Gustafsson   +9 more
doaj   +1 more source

Intestinal macromolecular transport supporting adaptive immunity [PDF]

open access: yes, 2019
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core   +2 more sources

Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. [PDF]

open access: yesPLoS ONE, 2009
The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis.
David H Tompkins   +7 more
doaj   +1 more source

Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF [PDF]

open access: yes, 2013
Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases.
Albanese CT   +15 more
core   +3 more sources

Goblet Cell Carcinoma of the Appendix: A Case Report on Goblet Cell Carcinoid

open access: yesHCA Healthcare Journal of Medicine, 2020
Description Goblet cell carcinoid of the appendix is a rare neoplasm with histological features of both neuroendocrine and adenocarcinomas. The combination of its aggressive behavior, infrequent occurrence, and variable clinical presentation convolutes the management of this tumor.
Sheliza, Kabani   +3 more
openaire   +3 more sources

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