Results 151 to 160 of about 328,019 (196)
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The pancreas of syrian golden hamsters
International journal of pancreatology, 1989We examined the effects of aging on the uptake of tritiated thymidine (3H-TdR) by the different cell types of the pancreas of the Syrian golden hamster. Animals, 8-22-wk-old, received 3H-TdR (2 microCi/gm) intraperitoneally and were sacrificed 1 h later. Pancreatic tissue from each animal was processed for autoradiography.
L, Rosenberg, W P, Duguid, A I, Vinik
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Tumorigenicity of cyclic nitrosamines in Syrian golden hamsters
Zeitschrift f�r Krebsforschung, 1970Nitrosoazetidine and nitrosoheptamethyleneimine have been tested by feeding in drinking water to Syrian golden hamsters. Nitrosoazetidine appeared noncarcinogenic in this species. Nitrosoheptamethyleneimine was strongly carcinogenic, producing tumors in a large proportion of the animals mainly in the forestomach, esophagus, larynx, pharynx, nasal ...
W, Lijinsky +3 more
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Toxicokinetics ofN-nitrosodimethylamine in the Syrian golden hamster
Archives of Toxicology, 1990The single-dose toxicokinetics of N-nitrosodimethylamine (NDMA) has been characterized in 8-week-old male Syrian golden hamsters by analysis using high performance liquid chromatography of serial blood samples. An i.v. bolus dose of 4.2 mumols/kg [14C]NDMA revealed biphasic first-order elimination with a terminal half-life of 8.7 +/- 1.0 min (mean ...
A J, Streeter +3 more
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The effect of 1-methoxypropylpropylnitrosamine in Syrian golden hamsters
Zeitschrift f�r Krebsforschung und Klinische Onkologie, 1977The carcinogenicity of the alpha-dipropylnitrosamine (DPN) methyl-ether, 1-methoxypropylpropylnitrosamine (1-MPPN), was investigated in Syrian hamsters for comparison with the effect of the alpha-DPN acetylester, 1-acetoxypropylpropylnitrosamine (1-APPN). It seemed possible that 1-MPPN, 1-APPN and DPN could form a common intermediate. However, contrary
J, Althoff, C, Grandjean, B, Gold
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Uptake of sidestream smoke by syrian golden hamsters
Toxicology Letters, 1987An inhalation bioassay with Syrian golden hamsters is being conducted to evaluate the toxic and carcinogenic potential of cigarette sidestream smoke (SS) relative to mainstream smoke (MS). A Hamburg II smoking machine is used to deliver MS by nose-only exposure to hamsters and a modification allows for the simultaneous collection of SS for whole-body ...
N J, Haley +3 more
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The Pathology of Proliferative Ileitis of the Golden Syrian Hamster
Pathologia veterinaria, 1967Lesions of an acute and chronic ileitis of hamsters were studied. A total of 92 animals between 6 and 12 weeks old was examined. Morbidity and mortality rates were 25 to 60% and 90% respectively. The initial lesion was epithelial hyperplasia of the ileal mucosa. Severe inflammatory changes in the ileum and adjacent structures were secondary.
A D, Boothe, N F, Cheville
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Anthrax vaccine efficacy in golden Syrian hamsters
Vaccine, 2002The efficacy of a licensed human anthrax vaccine (anthrax vaccine adsorbed, AVA) was tested in golden Syrian hamsters against a virulent Bacillus anthracis spore challenge. Groups of golden Syrian hamsters were vaccinated at either 0 and 4 weeks or 0, 4 and 8 weeks, then challenged subcutaneously (s.c.) at 10 weeks with spores of various B.
P F, Fellows +4 more
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Induction of Nesidioblastosis Will Reverse Diabetes in Syrian Golden Hamster
Diabetes, 1988Nesidioblastosis, which is the formation of new islets and the differentiation of cells within the islets, represents part of the spectrum of hyperfunctioning states of the islets of Langerhans at the clinical level. Nesidioblastosis in the Syrian golden hamster can be induced by wrapping the head of the pancreas with cellophane tape.
L, Rosenberg +3 more
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Developmental toxicology of acetonitrile in the syrian golden hamster
Teratology, 1983AbstractPregnant hamsters were exposed to acetonitrile by inhalation, ingestion, or ip injection during the early primitive streak stage of embryogenesis. Inhalation of 1,800 or 3,800 ppm acetonitrile for 60 min failed to induce malformations in the near‐term offspring whereas inhalation of 5,000 or 8,000 ppm acetonitrile was associated with production
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Conditioned defeat in the Syrian golden hamster (Mesocricetus auratus)
Behavioral and Neural Biology, 1993When singly housed under laboratory conditions, male Syrian golden hamsters routinely attack novel conspecific intruders introduced into their home cages. As we report here, after being repeatedly defeated by a larger, more aggressive intruder, such normal territorial aggression on the part of the resident hamsters is replaced by defensive behavior and
M, Potegal +3 more
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