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Golden Syrian Hamster Models for Cancer Research [PDF]

Cells, 2022
The golden Syrian hamster (Mesocricetus auratus) has long been a valuable rodent model of human diseases, especially infectious and metabolic diseases. Hamsters have also been valuable models of several chemically induced cancers such as the DMBA-induced oral cheek pouch cancer model.
Zhongde Wang, Wang Zhongde
exaly   +6 more sources

Evaluation of Immunogenicity and Clinical Protection of SARS-CoV-2 S1 and N Antigens in Syrian Golden Hamster [PDF]

Vaccines, 2022
The novel coronavirus (SARS-CoV-2) epidemic continues to be a global public crisis affecting human health. Many research groups are developing different types of vaccines to suppress the spread of SARS-CoV-2, and some vaccines have entered phase III ...
Heng Zhao, Pingfang Cui, Guörun Jiang   +2 more
exaly   +4 more sources

Comprehensive Transcriptome Analyses of the Fructose-Fed Syrian Golden Hamster Liver Provides Novel Insights into Lipid Metabolism. [PDF]

PLoS One, 2016
Dyslipidemia has been widely proven to contribute to cardiovascular diseases and other metabolic disorders, especially in insulin resistance and type 2 diabetes.
Li Z, Xiong C, Mo S, Tian H, Yu M, Mao T, Chen Q, Luo H, Li Q, Lu J, Zhao Y, Li W.   +11 more
europepmc   +4 more sources

Efficacy of Plant-Made Human Recombinant ACE2 against COVID-19 in a Golden Syrian Hamster Model [PDF]

Viruses, 2023
Coronavirus disease 2019 (COVID-19) is a novel infectious respiratory disease caused by SARS-CoV-2. We evaluated the efficacy of a plant-based human recombinant angiotensin-converting enzyme 2 (hrACE2) and hrACE2-foldon (hrACE2-Fd) protein against COVID ...
Sung-Chul Lim, Dong-Min Kim, Ju-Hyung Lee   +2 more
exaly   +4 more sources

Adrenocortical Adenocarcinoma in a Syrian Golden Hamster (Mesocricetus auratus) With Suspected Hyperadrenocorticism. [PDF]

Vet Med Sci
Although adrenal gland tumours are among the most common neoplasms in hamsters, few cases have been reported. A 2‐year‐old intact female pet golden hamster (Mesocricetus auratus) was initially presented with marked non‐pruritic alopecia of the ...
Billaux MF, Vieu S, Lecomte A, Cuvelier M, Rohel M, Abadie J, Soetart N.   +6 more
europepmc   +3 more sources

Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster [PDF]

Emerging Microbes and Infections, 2021
Reinfections with SARS-CoV-2 have already been documented in humans, although its real incidence is currently unknown. Besides having a great impact on public health, this phenomenon raises the question of immunity generated by a single infection is ...
Albert Bensaid, Julia Vergara-Alert, Jordi Rodón   +2 more
exaly   +5 more sources

Dietary-Induced Elevations of Triglyceride-Rich Lipoproteins Promote Atherosclerosis in the Low-Density Lipoprotein Receptor Knockout Syrian Golden Hamster. [PDF]

Front Cardiovasc Med, 2021
Elevated triglycerides are associated with an increased risk of cardiovascular disease (CVD). Therefore, it is very important to understand the metabolism of triglyceride-rich lipoproteins (TRLs) and their atherogenic role in animal models.
Lin X, Ma P, Yang C, Wang J, He K, Chen G, Huang W, Fan J, Xian X, Wang Y, Liu G.   +10 more
europepmc   +2 more sources

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9. [PDF]

Animal Model Exp Med
Background The golden Syrian hamster is a valuable animal model for studying carcinogenesis, metabolic disorders, cardiovascular diseases, and viral infections due to its biological and pathological similarities to humans.
Chen W, Zhang X, Fan R, Li X, Guan F, Wan G, Kong W, Qi X, Pan S, Shi S, Su Y, Gao S, Huang W, Xian X, Liu J, Wang Y, Ma Y.   +16 more
europepmc   +2 more sources

Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models. [PDF]

Dis Model Mech, 2022
Jeong H, Woo Lee Y, Park IH, Noh H, Kim SH, Kim J, Jeon D, Jang HJ, Oh J, On D, Uhm C, Cho K, Oh H, Yoon S, Seo JS, Kim JJ, Seok SH, Lee YJ, Hong SM, An SH, Yeon Kim S, Kim YB, Hwang JY, Lee HJ, Kim HB, Jeong DG, Song D, Song M, Park MS, Choi KS, Park JW, Seo JY, Yun JW, Shin JS, Lee HY, Nam KT, Seong JK.   +36 more
europepmc   +2 more sources

Histopathological and immunohistochemical characterization of lesions in the golden Syrian hamster model of Nipah virus infection (Bangladesh strain). [PDF]

Front Vet Sci
Nipah virus (NiV) is recognised as a priority pathogen with pandemic potential by the World Health Organisation (WHO). The NiV-Bangladesh strain (NiV-B) has been associated with recent outbreaks in different districts of Bangladesh and the state of ...
Swan K, Salguero FJ, Bird A, Hunter L, Kennard C, Findlay-Wilson S, Kennedy E, Kempster S, Almond N, Dowall S, Ruedas-Torres I.   +10 more
europepmc   +2 more sources