Golden Syrian Hamster Models for Cancer Research
Cells, 2022 The golden Syrian hamster (Mesocricetus auratus) has long been a valuable rodent model of human diseases, especially infectious and metabolic diseases. Hamsters have also been valuable models of several chemically induced cancers such as the DMBA-induced
Zhongde Wang
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Pathogens, 2023 Animal models of influenza are important in preclinical research for the study of influenza infection and the assessment of vaccines, drugs and therapeutics.
Kathryn A Ryan +2 more
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Comprehensive Transcriptome Analyses of the Fructose-Fed Syrian Golden Hamster Liver Provides Novel Insights into Lipid Metabolism. [PDF]
PLoS ONE, 2016 Dyslipidemia has been widely proven to contribute to cardiovascular diseases and other metabolic disorders, especially in insulin resistance and type 2 diabetes.
Ziyang Li +11 more
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Dietary-Induced Elevations of Triglyceride-Rich Lipoproteins Promote Atherosclerosis in the Low-Density Lipoprotein Receptor Knockout Syrian Golden Hamster [PDF]
Frontiers in Cardiovascular Medicine, 2021 Elevated triglycerides are associated with an increased risk of cardiovascular disease (CVD). Therefore, it is very important to understand the metabolism of triglyceride-rich lipoproteins (TRLs) and their atherogenic role in animal models.
Xiao Lin +10 more
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Evaluation of Immunogenicity and Clinical Protection of SARS-CoV-2 S1 and N Antigens in Syrian Golden Hamster [PDF]
Vaccines, 2022 The novel coronavirus (SARS-CoV-2) epidemic continues to be a global public crisis affecting human health. Many research groups are developing different types of vaccines to suppress the spread of SARS-CoV-2, and some vaccines have entered phase III ...
Zhenye Niu +13 more
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Translational insights into Long-COVID: evaluation of preclinical animal models along the lung-brain-immune axis with focus on Golden Syrian Hamsters [PDF]
Journal of NeuroinflammationLong-COVID, also referred to as post-acute sequelae of COVID-19 (PASC), is a heterogeneous disorder encompassing more than 200 reported symptoms that commonly affect the respiratory and nervous systems.
Narendra Kumar +5 more
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Adrenocortical Adenocarcinoma in a Syrian Golden Hamster (Mesocricetus auratus) With Suspected Hyperadrenocorticism [PDF]
Veterinary Medicine and ScienceAlthough adrenal gland tumours are among the most common neoplasms in hamsters, few cases have been reported. A 2‐year‐old intact female pet golden hamster (Mesocricetus auratus) was initially presented with marked non‐pruritic alopecia of the ...
Mathilde Firmin Billaux +6 more
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Protection Against Reinfection With D614- or G614-SARS-CoV-2 Isolates in Golden Syrian Hamster
Emerging Microbes and Infections, 2021 Reinfections with SARS-CoV-2 have already been documented in humans, although its real incidence is currently unknown. Besides having a great impact on public health, this phenomenon raises the question of immunity generated by a single infection is ...
Albert Bensaid +2 more
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Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9 [PDF]
Animal Models and Experimental MedicineBackground The golden Syrian hamster is a valuable animal model for studying carcinogenesis, metabolic disorders, cardiovascular diseases, and viral infections due to its biological and pathological similarities to humans.
Wei Chen +16 more
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Pathology and Host-Pathogen Interactions in a Golden Syrian Hamster Model of Nipah Virus Infection
Frontiers in Veterinary ScienceNipah virus (NiV) is recognized as one of the key pathogens with pandemic potential. We have recently established a NiV hamster model, which reproduces a highly similar disease to that observed in human cases, including respiratory and neurological signs
Stuart D Dowall +1 more
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