Results 41 to 50 of about 328,019 (200)

Diet-induced obesity and hypercholesterolemia in the Golden Syrian hamster.

, 2015
Whole-body fat mass (g), free-fed blood lipid and insulin levels of hamsters fed high fat-high carbohydrate (HPFS) palatable diet with 0.5% cholesterol supplementation for 12 weeks.
Louise S. Dalbøge (420563), Gitte Hansen (521571), Katrine Fabricius (782439), Niels Vrang (420564), Henrik B. Hansen (782440), Jacob Jelsing (420565), Philip J. Pedersen (782438)   +6 more
core   +1 more source

Bio F₁B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism

Nutrition & Metabolism, 2007
Background Bio F1B hamster is an inbred hybrid strain that is highly susceptible to diet-induced atherosclerosis. We previously reported that feeding a high fat fish oil diet to Bio F1B hamster caused severe hyperlipidaemia. In this study we compared the
Cornish Marion L, Cheema Sukhinder
doaj   +1 more source

Social context modulates food hoarding in Syrian hamsters

International Journal of Psychological Research, 2016
The effect of the presence of a con-specific in the temporal organization of food hoarding was studied in two varieties of Syrian hamster (Mesocricetus auratus): golden and long-haired. Four male hamsters of each variety were used.
Bibiana Montoya, Germán Gutiérrez
doaj   +3 more sources

Validation of Stable Housekeeping Genes for Quantitative Real Time PCR in Golden Syrian Hamster

, 2020
Background: Golden Syrian hamster (GSH) have many advantages as animal models in preclinical research, but their application is currently limited by the lack of standardized techniques for analyzing gene expression.
Peng, Ying, Wang, Jian-yao, Huang, Sheng-nan, Guo, Hao-ran, Wang, Ya-chao, Miao, Jin-Xin, Robl, Nick, Song, Shao-he, Li, Xiu-min, Sheng-nan Huang, Jian-yao Wang, Shao-he Song, Hao-ran Guo, Xiu-min Li, Nick Robl, Ying Peng, Ya-chao Wang, Jin-xin Miao   +17 more
core   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

The ventral striatum of the Syrian hamster

, 1999
The Syrian hamster, Mesocricetus auratus, was first used in laboratory experiments some fifty years ago in the Middle East, from animals captured in the wild.
LUKE R. JOHNSON, Wood, Ruth I., Johnson, Luke R., RUTH I. WOOD   +3 more
core   +1 more source

Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis

Animal Research and One Health, EarlyView.
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong, Ning Liu, Weining Kong, Xiang Gao, Feifei Guan, Shan Gao, Yuanwu Ma   +6 more
wiley   +1 more source

Modulatory effects of rutin on biochemical and hematological parameters in hypercholesterolemic Golden Syrian hamsters

Anais da Academia Brasileira de Ciências, 2009
Flavonoids have been reported to exhibit several pharmacological properties, mainly in cardiovascular and inflammatory diseases. In the present study, we observed that rutin, a known glycosylated flavonoid isolated from Dimorphandra mollis, had a ...
Alexandre Kanashiro, Daiani C.O. Andrade, Luciana M. Kabeya, Walter M. Turato, Lucia H. Faccioli, Sérgio A. Uyemura, Yara M. Lucisano-Valim   +6 more
doaj   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

Journal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira, Rogerio Salvini, Eloisa Dutra Caldas   +2 more
wiley   +1 more source