Results 61 to 70 of about 328,019 (200)

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 8, Page 1548-1566, August 2026.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji   +2 more
wiley   +1 more source

Conformational Stability of Syrian Hamster Prion Protein PrP(90−231)

open access: yes, 2016
Conformational Stability of Syrian Hamster Prion Protein PrP(90 ...
Teresa J. T. Pinheiro (198296)   +6 more
core   +1 more source

Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes

open access: yesJournal of Lipid Research, 2000
We studied the biogenesis of apolipoprotein B (apoB) in primary hepatocytes isolated from hamster liver, an animal model with striking resemblance to humans in lipoprotein metabolism. Hamster hepatocytes were found to assemble and secrete apoB-containing
Changiz Taghibiglou   +6 more
doaj   +1 more source

Anticancer and Anti‐Inflammatory Potential of Betalains: A Systematic Review on Preclinical Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Betalains derived from diverse natural sources, including beetroot (Beta vulgaris), Opuntia ficus‐indica, yellow prickly pear, and Atriplex hortensis “rubra” leaf and seed extracts, as well as purified betalains (amaranthin, celosianin, betanin, betaxanthins, and related derivatives), exhibit significant anticancer and anti‐inflammatory activities in ...
Aroob Fatima   +7 more
wiley   +1 more source

7,12-Dimethylbenz[a]anthracene-induced 'early' squamous cell carcinoma in the golden syrian hamster: Evaluation of an animal model and comparison with 'early' forms of human squamous cell carcinoma in the upper aero-digestive tract

open access: yes, 1996
To test and optimize photodynamic therapy of early cancers in the upper aero-digestive tract and oesophagus, we sought an appropriate animal model, which was found in the 7,12-dimethylbenz[a]anthracene-induced early squamous cell carcinoma in the Golden ...
Savary, J. F.   +4 more
core   +1 more source

Reduced-Fat Response of Lactobacillus casei subsp. casei SY13 on a Time and Dose-Dependent Model

open access: yesFrontiers in Microbiology, 2018
A reduced-fat effect of probiotics was primarily derived functionally rather than structurally, and we investigated the ultra-structural aspect of the gut mucosa in Syrian golden hamsters with high-fat diet by feeding with Lactobacillus casei subsp ...
Zhenhu Jia   +4 more
doaj   +1 more source

OG716: Designing a fit-for-purpose lantibiotic for the treatment of Clostridium difficile infections. [PDF]

open access: yesPLoS ONE, 2018
Lantibiotics continue to offer an untapped pipeline for the development of novel antibiotics. We report here the discovery of a novel lantibiotic for the treatment of C. difficile infection (CDI).
Johan A Kers   +6 more
doaj   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

open access: yesImmunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros   +5 more
wiley   +1 more source

Tumours of the lower respiratory tract

open access: yes, 2022
S.189-222In attempts to find appropriate animal models for human lung cancer, many experimental studies have used rats or mice treated with chemicals, viruses or radiation. Since the successful induction of tumours in the respiratory system of the Syrian
Dungworth, D.L.   +3 more
core   +1 more source

A Histological Study of the Pigment Development in the Skin of the Syrian Golden Hamster and the Albino Hamster With Particular Attention to the Ear

open access: yes, 1960
I. INTRODUCTIONThe skin of the Syrian golden hamster, Mesocricetus auratus (L.) is without color at birth, and apparently without hair covering, but within a few days the animal acquires a grayish-brown coat.
Tice, Mary Claudia
core   +1 more source

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