Results 61 to 70 of about 7,779 (204)

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Therapeutic Efficacy of Indole‐3‐Carbinol Against SARS‐CoV‐2‐Induced Acute Respiratory Distress Syndrome: A Dual Antiviral and Anti‐Inflammatory Approach in a Golden Syrian Hamster Model

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT SARS‐CoV‐2 has caused a global pandemic, resulting in over two million deaths and creating an urgent need for effective treatments. Severe COVID‐19 is frequently complicated by respiratory failure and acute respiratory distress syndrome (ARDS), the primary drivers of mortality.
Centofanti Federica, Rizzacasa Barbara, Latini Andrea, Biancolella Michela, Pocci Marco, Servadei Francesca, Scimeca Manuel, Mauriello Alessandro, Bernadett Palyi, Daniel Deri, Berenike Novak, Zoltan Kis, Claudia Filippone, Pier Paolo Pandolfi, Novelli Giuseppe   +14 more
wiley   +1 more source

Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes

Journal of Lipid Research, 2000
We studied the biogenesis of apolipoprotein B (apoB) in primary hepatocytes isolated from hamster liver, an animal model with striking resemblance to humans in lipoprotein metabolism. Hamster hepatocytes were found to assemble and secrete apoB-containing
Changiz Taghibiglou, Debbie Rudy, Stephen C. Van Iderstine, Andrea Aiton, Dora Cavallo, Raphael Cheung, Khosrow Adeli   +6 more
doaj   +1 more source

Análise ontogenética da interação lúdica e preferências por parceiros em filhotes de hamster dourado (Mesocricetus auratus) / [PDF]

, 1998
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências ...
Calegaro, Marco Montarroyos
core  

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

Molecular Microbiology, Volume 126, Issue 1, Page 98-110, July 2026.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan, Sourav Roy, Revathi Govind   +2 more
wiley   +1 more source

Análise da responsividade materna de hamsters dourados (Mesocricetus auratus) e ratos albinos (Rathus norvegicus) :: mudanças no comportamento nas fases pré e pós-parto / [PDF]

, 1997
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.As mães roedores exibem algumas mudanças comportamentais que podem estar associadas à estimulação proporcionada pelos filhotes ou à fatores fisiológicos ...
Albuquerque, Cláudia Almeida Coelho de
core  

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

eFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy, Abdelaali Balahbib, Meriem El Fessikh, Saïd Gharby, Nasreddine El Omari, Waleed Al Abdulmonem, Gokhan Zengin, Abdelhakim Bouyahya   +7 more
wiley   +1 more source

Reduced-Fat Response of Lactobacillus casei subsp. casei SY13 on a Time and Dose-Dependent Model

Frontiers in Microbiology, 2018
A reduced-fat effect of probiotics was primarily derived functionally rather than structurally, and we investigated the ultra-structural aspect of the gut mucosa in Syrian golden hamsters with high-fat diet by feeding with Lactobacillus casei subsp ...
Zhenhu Jia, Zhenhu Jia, Xiaoyang Pang, Xiaoyang Pang, Jiaping Lv   +4 more
doaj   +1 more source

OG716: Designing a fit-for-purpose lantibiotic for the treatment of Clostridium difficile infections. [PDF]

PLoS ONE, 2018
Lantibiotics continue to offer an untapped pipeline for the development of novel antibiotics. We report here the discovery of a novel lantibiotic for the treatment of C. difficile infection (CDI).
Johan A Kers, Anthony W DeFusco, Jae H Park, Jin Xu, Mark E Pulse, William J Weiss, Martin Handfield   +6 more
doaj   +1 more source

Photodynamic therapy for cancer of the pancreas [PDF]

, 2002
Background: Few pancreatic cancers are suitable for surgery and few respond to chemoradiation. Photodynamic therapy produces local necrosis of tissue with light after prior administration of a photosensitising agent, and in experimental studies can be ...
Lovat, L.B., Hatfield, A.W.R., Rogowska, A.Z., Wyld, P., Gillams, A., Jones, L., Bown, S.G., Ripley, P., Whitelaw, D.E., Lees, W.R.   +9 more
core