This review focuses on spatial omics, covering the introduction and comparison of technology platforms, explanation and recommendation of algorithm ecology, demonstration of biological applications, and prospect of large models. It aims to help researchers in the interdisciplinary field of spatial omics quickly understand the current situation and ...
Haoxiu Wang +26 more
wiley +1 more source
Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters [PDF]
The Syrian golden hamster is an attractive animal for research on infectious diseases and other diseases. We report here the sequencing, assembly, and annotation of the Syrian hamster transcriptome.
Aurora, Rajeev +4 more
core +1 more source
Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand +6 more
wiley +1 more source
Circulating Foamy Macrophages in the Golden Syrian Hamster (Mesocricetus auratus) Model of Leptospirosis [PDF]
Leptospirosis is a world-wide zoonotic disease caused by pathogenic Leptospira and can be asymptomatic or can cause clinical signs ranging from influenza-like to multi-organ failure and death in severe cases. While species and strain specificity can play
Palmer, Mitchell V. +6 more
core +1 more source
ABSTRACT The lack of a dose–response model for Clostridioides difficile, attributed to insufficient human data, challenges effective C. difficile infection (CDI) risk management. This study presents a novel murine‐derived dose–response model for C.
Elizabeth N. Paddy +2 more
wiley +1 more source
The feasibility of establishing a hamster model for HBV infection: in vitro evidence
Chronic hepatitis B virus (HBV) infection remains a significant public health burden with no cure currently available. The research to cure HBV has long been hampered by the lack of immunocompetent small animal models capable of supporting HBV infection.
Hu Zhang +4 more
doaj +1 more source
A Histological Study of the Pigment Development in the Skin of the Syrian Golden Hamster and the Albino Hamster With Particular Attention to the Ear [PDF]
I. INTRODUCTIONThe skin of the Syrian golden hamster, Mesocricetus auratus (L.) is without color at birth, and apparently without hair covering, but within a few days the animal acquires a grayish-brown coat.
Tice, Mary Claudia
core
A Novel Cancer Syndrome Caused by KCNQ1-Deficiency in the Golden Syrian Hamster [PDF]
BACKGROUND: The golden Syrian hamster is an emerging model organism. To optimize its use, our group has made the first genetically engineered hamsters. One of the first genes that we investigated is KCNQ1 which encodes for the KCNQ1 potassium channel and
Li, Rong +7 more
core +2 more sources
Objective Quaking‐induced conversion (QuIC) tests, which detect prion‐seeding activity in cerebrospinal fluid (CSF), have markedly advanced the antemortem diagnosis of prion diseases such as Creutzfeldt‐Jakob disease (CJD). These tests provide high diagnostic accuracy and enable timely differentiation from other rapidly progressive neurodegenerative ...
Jennifer Myskiw +13 more
wiley +1 more source
Morphological characteristics of the cutaneus covering of the Syrian golden hamster [PDF]
The purpose of this work was the presentation of morphological data of the structure of the skin of a Syrian hamster, actively used as an experimental animal to create a model of a burn wound.
Бычков, В. Г. +5 more
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