ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira +2 more
wiley +1 more source
Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2
Neutrophil extracellular traps (NETs) have been identified as one pathogenetic trigger in severe COVID-19 cases and therefore well-described animal models to understand the influence of NETs in COVID-19 pathogenesis are needed.
Kathrin Becker +14 more
doaj +1 more source
Demodicosis in a Golden (Syrian) hamster (Mesocricetus auratus) [PDF]
A two year old male Golden (Syrian) hamster (Mesocricetus auratus) was presented with a history of alopecia on the dorso-lumbosacral area and on the back, lethargy, anorexia and severe pruritus.
Haydardedeoğlu, A. Evren +6 more
core
Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe +4 more
wiley +1 more source
Efeitos de diferentes períodos de isolamento social sobre o comportamento de hamsters dourados (Mesocricetus auratus) a curto e longo prazo [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Determinação dos efeitos de diferentes períodos de isolamento sobre o comportamento social do indivíduo, procurando
Rau, Débora Driemeyer Wilbert
core
Hypothalamic ventricular ependymal thyroid hormone deiodinases are an important element of circannual timing in the Siberian hamster (Phodopus sungorus) [PDF]
Peer ...
de Vries Emmely M. +27 more
core +1 more source
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang +9 more
wiley +1 more source
Protective effect of coumarin on cell surface glycoconjugates abnormalities during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis [PDF]
Aims: The major aims of the present study was to focus the protective effect of coumarin on cell surface glycoconjugates abnormalities during 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis. Methods: DMBA painting in the
Nagarethinam Baskaran +2 more
doaj
Cardiovascular disease is the leading cause of morbidity and mortality in both developed and developing countries, in which atherosclerosis triggered by dyslipidemia is the major pathological basis.
Liu George +4 more
doaj +1 more source
Anticancer and Anti‐Inflammatory Potential of Betalains: A Systematic Review on Preclinical Studies
Betalains derived from diverse natural sources, including beetroot (Beta vulgaris), Opuntia ficus‐indica, yellow prickly pear, and Atriplex hortensis “rubra” leaf and seed extracts, as well as purified betalains (amaranthin, celosianin, betanin, betaxanthins, and related derivatives), exhibit significant anticancer and anti‐inflammatory activities in ...
Aroob Fatima +7 more
wiley +1 more source

