Results 141 to 150 of about 228,960 (304)
Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi +10 more
wiley +1 more source
Synthesis and Docking Studies of Glycolipids Inspired by Bacteroides fragilis Lipid A
MoleculesBacteroides fragilis, a prominent commensal of the human gut microbiota, plays a vital role in immune system regulation through its capsular polysaccharide A (PSA), which requires a glycolipid anchor structurally reminiscent of lipid A.
Davie Kenneth +6 more
doaj +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr +7 more
wiley +1 more source
In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice
Advanced NanoBiomed Research, EarlyView.Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin +22 more
wiley +1 more source
Synthesis and Characterization of Benzo[1,2-b:4,3-b’]dithiophene-Based Biaryls
MolbankThe synthesis of three biaryl systems containing the benzo[1,2-b:4,3-b’] framework was accomplished through the Suzuki–Miyaura cross-coupling reaction between 1-bromobenzo[1,2-b:4,3-b’]dithiophene and easily available polycyclic aromatic hydrocarbon ...
Valentina Pelliccioli +4 more
doaj +1 more source
La doctrina del neurón: Teorías y hechos
, 1907 Fil: Golgi, Camilo.
Golgi, Camilo
core +2 more sources
Angewandte Chemie, EarlyView.CYB5R3 wird als mutmaßlicher Elektronentransferpartner von Viperin (RSAD2) identifiziert, was erklärt, warum die ER‐Lokalisation für die antivirale Aktivität erforderlich ist. Dieses Wissen ermöglichte die Entwicklung immunstiller, katalytisch selbstversorgender antiviraler Restriktionsfaktor‐Enzyme (iCAREs), die ein antivirales Nukleosidtriphosphat ...
Mengdi Wu +16 more
wiley +1 more source
Exit of different cargoes from the Golgi and their post-Golgi trafficking [PDF]
BIO Web of ConferencesBeznoussenko Galina, Mironov Alexander
doaj +1 more source
Three-dimensional, correlative electron microscopy and immuno-labelling revealed new principles of the Golgi complex functioning [PDF]
BIO Web of ConferencesMironov Alexander, Beznoussenko Galina
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu +16 more
wiley +1 more source