Results 121 to 130 of about 214,335 (315)

Chemisorption vs. Physisorption in Perfluorinated Zn(II) Porphyrin–SnO₂ Hybrids for Acetone Chemoresistive Detection

Molecules
In this study, the integration of SnO2 with a perfluorinated Zn(II) porphyrin derivative, namely ZnTPPF20CN, was explored as a strategy to enhance the performance of chemoresistive sensors toward gaseous acetone detection.
Manuel Minnucci, Sara Oregioni, Eleonora Pargoletti, Gabriele Di Carlo, Francesca Tessore, Gian Luca Chiarello, Rocco Martinazzo, Mario Italo Trioni, Giuseppe Cappelletti   +8 more
doaj   +1 more source

The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. [PDF]

, 2001
Cargo selection and export from the endoplasmic reticulum is mediated by the COPII coat machinery that includes the small GTPase Sar1 and the Sec23/24 and Sec13/31 complexes.
Bannykh, Sergei, Balch, WE, William E. Balch, Aridor, M, Balch, William E, Fish, KN, Lippincott-Schwartz, J, Fish, Kenneth N, Lippincott-Schwartz, Jennifer, Meir Aridor, Weissman, Jacques, Sergei Bannykh, Jacques Weissman, Bannykh, S, Roberts, Theresa H, Weissman, J, Aridor, Meir, Jennifer Lippincott-Schwartz, Roberts, TH, Theresa H. Roberts, Kenneth N. Fish   +20 more
core   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Frontotemporal lobar degeneration complexity: atypical presentations and heterogeneous proteinopathies in five cases

Frontiers in Neuroscience
IntroductionFrontotemporal lobar degeneration (FTLD) encompasses heterogeneous clinical syndrome within the frontotemporal spectrum, where clinicopathological associations may be misleading.
Giulia Negro, Giulia Negro, Camilla Poloni, Valentina Medici, Chiara Calatozzolo, Alessandra Canazza, Riccardo Rocco Ferrari, Chiara Cutaia, Annalisa Davin, Tino Emanuele Poloni, Tino Emanuele Poloni   +10 more
doaj   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Targeting Drosophila Sas6 to mitochondria reveals its high affinity for Gorab

Biology Open, 2022
Levente Kovacs, Agnieszka Fatalska, David M. Glover   +2 more
doaj   +1 more source

Life Cycle Assessment of Swimming Goggles: Evaluating Environmental Impact and Consumer Awareness

Journal of Experimental and Theoretical Analyses
This study evaluates the environmental impact of swimming goggles through a Life Cycle Assessment (LCA), comparing virgin and recycled polycarbonate models.
Vasilissa Nikonova, Veronica Bortolotto, Costanza Bebber, Irene Presti, Gabriele Angelo Valtorta, Serena Biella, Claudia Letizia Bianchi   +6 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

The factory, the antenna and the scaffold: the three-way interplay between the Golgi, cilium and extracellular matrix underlying tissue function

Biology Open, 2023
Nicola L. Stevenson
doaj   +1 more source

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

Advanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng, Mengdie Cao, Hai Huang, Shuya Bai, Luyao Liu, Jingwen Liang, Haochen Cui, Qiaodan Zhou, Shiru Chen, Jiamei Jiang, Luoxia Liu, Zhou Luan, Wei Chen, Si Xiong, Ronghua Wang, Bin Cheng, Yuchong Zhao   +16 more
wiley   +1 more source