Results 171 to 180 of about 956,222 (367)

Thermally Driven Dynamic Behaviors in Polymeric Vesicles

open access: yesSmall, EarlyView.
Synthetic cells aim to mimic biological form, function, and behavior. In this article, the thermoresponsive properties of the polymer poly(ethylene oxide)‐poly(butylene oxide) are leveraged to create a range of polymeric synthetic cell systems on the nanoscale and microscale which possess a range of biomimetic properties, including cargo release ...
Matthew E. Allen   +6 more
wiley   +1 more source

AP2S1 regulates APP degradation through late endosome–lysosome fusion in cells and APP/PS1 mice

open access: yesTraffic, Volume 24, Issue 1, Page 20-33, January 2023., 2023
Fission events at endo‐lyso interface could be favored in the presence of AP2S1, which is reminiscent of membrane fission during endocytosis. In contrast, lack of AP2S1 may inhibit this process, and alternatively facilitate endo‐lyso fusion and content exchange, leading to lysosomal degradation of APP.
Qi‐Xin Wen   +11 more
wiley   +1 more source

Deciphering structural complexity of brain, joint, and muscle tissues using Fourier ptychographic scattered light microscopy

open access: yesVIEW, EarlyView.
This study introduces Fourier ptychographic scattered light microscopy (FP‐SLM). It combines Fourier ptychographic microscopy (FPM), which images large fields of view with high resolution, and computational scattered light imaging (ComSLI), which visualizes densely interwoven fibers.
Simon E. van Staalduine   +3 more
wiley   +1 more source

V‐ATPase Disassembly at the Yeast Lysosome‐Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging

open access: yesAging Cell, EarlyView.
H+‐translocating V‐ATPases are regulated by reversible disassembly in many cell types. In young yeast cells, V‐ATPases are assembled and the lysosome‐like vacuole is acidified, but as cells age, V‐ATPases disassemble, vacuolar pH increases, and lifespan is shortened. Both mutation of the V‐ATPase disassembly factor Oxr1 and caloric restriction preserve
Fiza Hashmi, Patricia M. Kane
wiley   +1 more source

STRUCTURE OF ISOLATED PLANT GOLGI APPARATUS REVEALED BY NEGATIVE STAINING [PDF]

open access: bronze, 1966
William P. Cunningham   +2 more
openalex   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

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