Results 1 to 10 of about 1,228,008 (299)
Signalling to and from the secretory pathway [PDF]
Journal of Cell Science, 2011 For growth, survival, communication and homeostasis, cells transport a large number of proteins to the plasma membrane and the extracellular medium by using the secretory pathway. Consequently, to adapt to the surrounding environment and the different intracellular contexts, the secretory pathway needs to accommodate and respond to a plethora of ...
Farhan H, Rabouille C
core +10 more sources
The Unfolded Protein Response as a Guardian of the Secretory Pathway
Cells, 2021 The endoplasmic reticulum (ER) is the major site of membrane biogenesis in most eukaryotic cells. As the entry point to the secretory pathway, it handles more than 10,000 different secretory and membrane proteins.
Toni Radanović, Robert Ernst
doaj +3 more sources
Secretory Pathway of Trypanosomatid Parasites [PDF]
Microbiology and Molecular Biology Reviews, 2002 SUMMARYThe Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause important diseases in humans. These include Trypanosoma brucei (the causative agent of African sleeping sickness and nagana in cattle), Trypanosoma cruzi (the causative agent of Chagas' disease in Central and South America), and Leishmania spp.
McConville, Malcolm J. +3 more
openaire +7 more sources
The secretory pathway kinases [PDF]
Biochimica Et Biophysica Acta - Proteins and Proteomics, 2015 Protein phosphorylation is a nearly universal post-translation modification involved in a plethora of cellular events. Even though phosphorylation of extracellular proteins had been observed, the identity of the kinases that phosphorylate secreted proteins remained a mystery until only recently.
Anju Sreelatha +2 more
exaly +3 more sources
A highly sensitive assay for monitoring the secretory pathway and ER stress. [PDF]
PLoS ONE, 2007 The secretory pathway is a critical index of the capacity of cells to incorporate proteins into cellular membranes and secrete proteins into the extracellular space.
Christian E Badr +3 more
doaj +3 more sources
The regulated secretory pathway in neuroendocrine cells [PDF]
Frontiers in Endocrinology, 2014 The regulated secretory pathway is a hallmark of neuroendocrine cells. This process comprises many sequential steps, which include ER-associated protein synthesis, post-translational modification of proteins in the Golgi complex, sorting and packing of secretory proteins into carrier granules, cytoskeleton-based granule transport towards the plasma ...
Rafael eVazquez-Martinez +1 more
doaj +4 more sources
The exocyst complex is an essential component of the mammalian constitutive secretory pathway [PDF]
Journal of Cell Biology, 2023 Amber Shun-Shion +2 more
exaly +2 more sources
Drosophila KDEL receptor function in the embryonic salivary gland and epidermis. [PDF]
PLoS ONE, 2013 Core components of the secretory pathway have largely been identified and studied in single cell systems such as the budding yeast S. cerevisiae or in mammalian tissue culture.
Elliott W Abrams +2 more
doaj +1 more source
Cells, 2020 The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic reticulum (ER) to the Golgi are still not well understood.
Sergio Lopez +8 more
doaj +1 more source
Frontiers in Plant Science, 2013 The secretory pathway of eukaryotic cells has an elaborated set of endomembrane compartments involved in the synthesis, modification and sorting of proteins and lipids.
Camilo ePatarroyo +2 more
doaj +1 more source