Results 11 to 20 of about 1,228,008 (299)

Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca2+ in Hansenula polymorpha. [PDF]

open access: yesPLoS ONE, 2015
Processes taking place in the secretory organelles require Ca2+ and Mn2+, which in yeast are supplied by the Pmr1 ion pump. Here we observed that in the yeast Hansenula polymorpha Ca2+ deficiency in the secretory pathway caused by Pmr1 inactivation is ...
Anastasia V Fokina   +4 more
doaj   +1 more source

secretory pathway

open access: yes, 2021
secretion is the movement of material from one point to another .
negar ebrahimi   +2 more
openaire   +2 more sources

The role of the lectin VIP36 in the early secretory pathway [PDF]

open access: yes, 2010
Lectins are of emerging importance for quality control and intracellular transport of glycoproteins in mammalian cells. One of the most prominent lectins involved in intracellular transport is ERGIC-53, which belongs to the family of L-type lectins ...
Reiterer, Veronika
core   +1 more source

Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

open access: yesNature Communications, 2020
The secretory pathway is used in the production of most biopharmaceuticals, but the associated biosynthetic costs are little understood. Here, the authors integrate the core secretory pathway into genome-scale metabolic models of human, mouse, and CHO ...
Jahir M. Gutierrez   +14 more
doaj   +1 more source

Visualization of protein-protein interactions in the secretory pathway of mammalian cells [PDF]

open access: yes, 2006
An increasing number of human disorders are being linked to mutations in components of the secretory pathway. One example is combined blood coagulation factor V and VIII deficiency, an autosomal recessive disorder leading to hemophilia due to markedly ...
Nyfeler, Beat
core   +1 more source

The key target of neuroprotection after the onset of ischemic stroke: secretory pathway Ca 2+ -ATPase 1

open access: yesNeural Regeneration Research, 2015
The regulatory mechanisms of cytoplasmic Ca 2+ after myocardial infarction-induced Ca 2+ overload involve secretory pathway Ca 2+ -ATPase 1 and the Golgi apparatus and are well understood.
Li-hua Li, Xiang-rong Tian, Zhi-ping Hu
doaj   +1 more source

Function of human surf4 in the early secretory pathway [PDF]

open access: yes, 2007
Transport along the early secretory pathway is mediated by vesicles that shuttle proteins and lipids between organelles. Highly organized machineries assure correct trafficking in anterograde and retrograde directions as well as homeostasis of the ...
Mitrovic, Sandra
core   +1 more source

Characterization of p28, a novel ERGIC/"cis"-Golgi protein, required for Golgi ribbon formation. pH measurements in the early secretory pathway "in vivo" [PDF]

open access: yes, 2008
The secretory pathway of mammalian cells consists of several compartments. Transport between these organelles is accomplished via vesicular carriers or maturation. For non abundant proteins it is thought that transport receptors help the proteins to exit
Kögler, Eva Jutta
core   +1 more source

Lectins and traffic in the secretory pathway [PDF]

open access: yesFEBS Letters, 2000
Evidence is accumulating that intracellular animal lectins play important roles in quality control and glycoprotein sorting along the secretory pathway. Calnexin and calreticulin in conjunction with associated chaperones promote correct folding and oligomerization of many glycoproteins in the endoplasmic reticulum (ER).
Hauri, H.   +3 more
openaire   +4 more sources

Ancestry and evolution of a secretory pathway serpin [PDF]

open access: yes, 2008
Kumar A, Ragg H. Ancestry and evolution of a secretory pathway serpin. BMC Evolutionary Biology. 2008;8(1): 250.Background:The serpin (serine protease inhibitor) superfamily constitutes a class of functionally highly diverse proteins usually encompassing
Hermann Ragg   +5 more
core   +1 more source

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