Results 191 to 200 of about 957,365 (341)

WNT5a export onto extracellular vesicles studied at single‐molecule and single‐vesicle resolution

The FEBS Journal, EarlyView.
WNT signaling, which orchestrates tissue development and homeostasis, is mediated by hydrophobic WNT proteins traveling from secreting to receiving cells on various carriers. Here, fusion constructs of fluorescent proteins with WNT5a were developed and functionally validated.
Antonia Schubert, Ajaree Mongkolsittisilp, Andrei Kobitski, Matthias Schulz, Oksana Voloshanenko, Meike Schaffrinski, Nadine Winkler, Michelle Neßling, Karsten Richter, Dominique Kranz, Karin Nienhaus, Dirk Jäger, Lorenz Trümper, Judith Büntzel, Claudia Binder, Gerd Ulrich Nienhaus, Michael Boutros   +16 more
wiley   +1 more source

Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure. [PDF]

Sci Rep
Wang Y, Cheng Y, Sun H, Wang Z, Chen N, Shi C, Liu H, Yang J, Xu Y.   +8 more
europepmc   +1 more source

Intracellular transport of the transmembrane glycoprotein G of vesicular stomatitis virus through the Golgi apparatus as visualized by electron microscope radioautography. [PDF]

, 1982
John Bergeron, Girish J. Kotwal, Gary M. Levine, Patricia Bilan, Richard A. Rachubinski, Melissa Shea Hamilton, G C Shore, H P Ghosh   +7 more
openalex   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Alteration in Golgi apparatus fragmentation related genes in human dilated cardiomyopathy. [PDF]

Sci Rep
González-Torrent I, Giménez-Escamilla I, Pérez-Carrillo L, Delgado-Arija M, Portolés M, Tarazón E, Roselló-Lletí E.   +6 more
europepmc   +1 more source

Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus. [PDF]

Biomolecules, 2023
Prikryl D, Marin M, Desai TM, Du Y, Fu H, Melikyan GB.   +5 more
europepmc   +1 more source

Membrane fusion and glycosylation in the rat hepatic Golgi apparatus. [PDF]

, 1982
Jacques Paiement, Richard A. Rachubinski, N M Ng Ying Kin, R Sikstrom, John Bergeron   +4 more
openalex   +1 more source

Insights into the Localization and Function of the Membrane Trafficking Regulator GNOM ARF-GEF at the Golgi Apparatus in Arabidopsis[W]

The Plant Cell, 2014
S. Naramoto, M. Otegui, N. Kutsuna, R. De Rycke, Tomoko Dainobu, Michael Karampelias, Masaru Fujimoto, E. Feraru, D. Miki, H. Fukuda, A. Nakano, J. Friml   +11 more
semanticscholar   +1 more source

Short coiled‐coil proteins from plants and metazoans – the ‘jacks of all trades’

The FEBS Journal, EarlyView.
Short coiled‐coil proteins from plants and metazoans—true ‘jacks of all trades’—play supporting but crucial roles in cellular stress response, metabolism, autophagy, and membrane dynamics. Despite their small size and modest sequence conservation, proteins like plant LSUs and metazoan SCOCs showcase remarkable functional versatility shaped by evolution,
Agnieszka Sirko, Jarosław Poznański, Marzena Sieńko   +2 more
wiley   +1 more source

Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network. [PDF]

Proc Natl Acad Sci U S A
Yoshimura SI, Sobajima T, Kunii M, Harada A.   +3 more
europepmc   +1 more source