Results 301 to 310 of about 956,222 (367)

Integrative Analysis of Dog Serum‐Derived CircRNA Expression and Disease Severity, Inflammatory and Cardiac Damage Biomarkers Related to Canine Parvoviral Enteritis

open access: yesVeterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Novel circRNA‐based biomarkers for inflammation, disease severity and cardiac damage were discovered in dogs with canine parvoviral enteritis. The obtained circRNAs participated in the entire CPV infection process, exhibited substantial links with infection occurrence and progression and have the potential to regulate infection pathogenesis.
Şükrü Değirmençay   +4 more
wiley   +1 more source

Production of yeast cell wall polysaccharides‐β‐glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 3, May 2025.
Abstract Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient‐rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single‐cell microorganisms like yeast.
Deniz Günal‐Köroğlu   +5 more
wiley   +1 more source

The Ever‐Expanding Influence of the Endothelial Nitric Oxide Synthase

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Nitric oxide (NO) generated by the endothelial NO synthase (eNOS) plays an essential role in the maintenance of vascular homeostasis and the prevention of vascular inflammation. There are a myriad of mechanisms that regulate the activity of the enzyme that may prove to represent interesting therapeutic opportunities.
Riham Rafea   +2 more
wiley   +1 more source

DCC in the cerebral cortex is required for cognitive functions in mouse

open access: yesBrain Pathology, Volume 35, Issue 3, May 2025.
Abstract Schizophrenia (SZ) is a highly heritable mental disorder, and genome‐wide association studies have identified the association between deleted in colorectal cancer (DCC) and SZ. Previous study has shown a lowered expression of DCC in the cerebral cortex of SZ patient.
Yun‐Qing Hu   +9 more
wiley   +1 more source

Cytoplasmic Vacuolization: A Fascinating Morphological Alteration From Cellular Stress to Cell Death

open access: yesCancer Science, Volume 116, Issue 5, Page 1181-1192, May 2025.
This review provides a thorough examination of contemporary studies on cytoplasmic vacuolization in mammalian cells, elucidating its etiology, origins, and molecular pathways. Additionally, it highlights the potential of CVACD as an innovative therapeutic strategy for cancer.
Xiaoxu Wen, Hongru Ma
wiley   +1 more source

Reliability of Brain Activity During a Supine Bilateral Leg Press and Association With Concurrent 3D Knee Joint Biomechanics

open access: yesEuropean Journal of Neuroscience, Volume 61, Issue 9, May 2025.
The current study established the leg press task as a reliable paradigm for investigating brain activity and concurrent knee joint kinematics. Furthermore, it identified a relationship between knee sagittal range of motion and brain activity in the right LOC and bilateral putamen, potentially reflecting enhanced sensorimotor integration and motor ...
HoWon Kim   +10 more
wiley   +1 more source

New insights in cellular senescence: The pituitary model

open access: yesJournal of Neuroendocrinology, Volume 37, Issue 5, May 2025.
Senescence is a pivotal process in pituitary tumorigenesis. Recent advances have elucidated the complex mechanisms by which key factors, including IL‐6, establish and maintain senescence in these tumors. Given the critical role of senescence and the development of novel techniques to detect senescent cells, the identification of biomarkers and the ...
Florencia Herbstein   +8 more
wiley   +1 more source

Hypoxia Disrupts Sex‐Specific Physiology and Gene Expression Leading to Decreased Fitness in the Estuarine Sea Anemone Nematostella vectensis

open access: yesMolecular Ecology, Volume 34, Issue 9, May 2025.
ABSTRACT Coastal seawater hypoxia is increasing in temperate estuaries under global climate change, yet it is unknown how low oxygen conditions affect most estuarine species. We found that hypoxia has increased since the 1990s in an estuary hosting the sea anemone Nematostella vectensis (Jacques Cousteau National Estuarine Research Reserve, New Jersey,
Benjamin H. Glass   +5 more
wiley   +1 more source

A multifunctional organelle coordinates phagocytosis and chlorophagy in a marine eukaryote phytoplankton Scyphosphaera apsteinii

open access: yesNew Phytologist, Volume 246, Issue 3, Page 1096-1112, May 2025.
Summary Mixotrophy via phagocytosis can have profound consequences for the survival of marine phytoplankton and the efficiency of carbon transfer in marine systems. Little is known about the cellular mechanisms that underly nutrient acquisition via prey uptake and processing in mixotrophic phytoplankton. We used confocal microscopy, flow cytometry, and
Julie A. Koester   +4 more
wiley   +1 more source

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