Results 71 to 80 of about 956,222 (367)

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

Science Signaling, 2015
Calcium released from the Golgi apparatus may promote receptor trafficking to the surface of cardiomyocytes. A distinct calcium store in cardiomyocytes In cardiomyocytes, contraction can be triggered by large influxes of calcium (Ca2+) into the cytoplasm
Zhaokang Yang, Hannah M. Kirton, David A. MacDougall, J. Boyle, J. Deuchars, B. Frater, S. Ponnambalam, M. Hardy, E. White, S. Calaghan, C. Peers, D. Steele   +11 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Toward Sustainable Photocatalysis: Addressing Deactivation and Environmental Impact of Anodized and Sol–Gel Photocatalysts

Advanced Sustainable Systems, EarlyView.
A life‐cycle evaluation of TiO2 photocatalysts for water purification compares the effectiveness of Sol–Gel vs anodic oxides in tetracycline mineralization, targeting deactivation, regeneration, and environmental impact from a cradle‐to‐grave perspective.
Maria Vittoria Diamanti, Manjunath V. Shinnur, MariaPia Pedeferri, Anna Maria Ferrari, Roberto Rosa, Daniela Meroni   +5 more
wiley   +1 more source

Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ-Secretase Activity

mBio, 2014
The route taken by papillomaviruses from the cell surface to the nucleus during infection is incompletely understood. Here, we developed a novel human papillomavirus 16 (HPV16) pseudovirus in which the carboxy terminus of the minor capsid protein L2 is ...
Wei Zhang, Teymur Kazakov, A. Popa, D. DiMaio   +3 more
semanticscholar   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

Golgi defect as a major contributor to lysosomal dysfunction

Frontiers in Cell and Developmental Biology
The Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell survival. Deficiencies in Golgi structure and function can profoundly impact lysosomal
Sarah R. Akaaboune, Yanzhuang Wang
doaj   +1 more source

Preferred states of the apparatus [PDF]

Pramana-Journal of Physics, Vol 78(2) , 2012 , pp 175-186, 2012
A simple one dimensional model for the system-apparatus interaction is analyzed. The system is a spin-1/2 particle, and its position and momentum degrees constitutes the apparatus. An analysis involving only unitary Schrodinger dynamics illustrates the nature of the correlations established in the system-apparatus entangled state. It is shown that even
arxiv   +1 more source

Phosphatidylinositol 4-phosphate in the Golgi apparatus regulates cell-cell adhesion and invasive cell migration in human breast cancer.

Cancer Research, 2014
Downregulation of cell-cell adhesion and upregulation of cell migration play critical roles in the conversion of benign tumors to aggressive invasive cancers.
E. Tokuda, T. Itoh, Junya Hasegawa, T. Ijuin, Y. Takeuchi, Y. Irino, Miki Fukumoto, T. Takenawa   +7 more
semanticscholar   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidan Chen   +21 more
wiley   +1 more source