Results 11 to 20 of about 18,240,259 (142)

Golgi Phosphoprotein 3 Regulates the Physical Association of Glycolipid Glycosyltransferases [PDF]

International Journal of Molecular Sciences, 2022
Glycolipid glycosylation is an intricate process that mainly takes place in the Golgi by the complex interplay between glycosyltransferases. Several features such as the organization, stoichiometry and composition of these complexes may modify their ...
Gonzalo Mardones, José Daniotti, Viviana A Cavieres   +2 more
exaly   +4 more sources

Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression [PDF]

Cellular Physiology and Biochemistry, 2018
Background/Aims: Golgi phosphoprotein 3 (GOLPH3) plays pro-malignancy roles in several types of cancer. However, the molecular mechanism underlying GOLPH3 promoting tumor progression remains poorly understood.
Dong Lu, Hao Zhang, Jiale Fu, Yanhua Qi, Xu Wang, Shishuang Wu, Xiuping Zhou, Rutong Yu   +7 more
doaj   +2 more sources

Comparative genomics analyses of Actinobacteriota identify Golgi phosphoprotein 3 (GPP34) as a widespread ancient protein family associated with sponge symbiosis [PDF]

Microbiome
Background Sponges harbor microbial communities that play crucial roles in host health and ecology. However, the genetic adaptations that enable these symbiotic microorganisms to thrive within the sponge environment are still being elucidated.
Cláudia Ferreira, Ilia Burgsdorf, Tzipora Perez, Gustavo Ramírez, Maya Lalzar, Dorothée Huchon, Laura Steindler   +6 more
doaj   +2 more sources

Retraction Note: The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-κB signaling pathway [PDF]

Journal of Experimental & Clinical Cancer Research
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-017-0607-0.
Shanyang He, Gang Niu, Jianhong Shang, Yalan Deng, Zhiyong Wan, Cai Zhang, Zeshan You, Hongwei Shen   +7 more
doaj   +2 more sources

Protosappanin B enhances the chemosensitivity of 5-fluorouracil in colon adenocarcinoma by regulating the LINC00612/microRNA-590-3p/Golgi phosphoprotein 3 axis [PDF]

Discover Oncology
Background 5-fluorouracil (5-FU) is conventionally used in chemotherapy for colon adenocarcinomas. Acquired resistance of 5-FU remains a clinical challenge in colon cancer, and efforts to develop targeted agents to reduce resistance have not yielded ...
Zhongshi Hong, Yachen Li, Mingliang Chen, Xiaojing Chen, Xian Deng, Yuze Wu, Chunxiao Wang, Chengzhi Qiu   +7 more
doaj   +2 more sources

The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner. [PDF]

PLoS ONE, 2019
Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown.
Cecilia Arriagada, Charlotte Luchsinger, Alexis E González, Tomás Schwenke, Gloria Arriagada, Hugo Folch, Pamela Ehrenfeld, Patricia V Burgos, Gonzalo A Mardones   +8 more
doaj   +2 more sources

Molecular regulation and physiological role of GOLPH3-mediated Golgi retention [PDF]

Nature Communications
The Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long been debated.
Anastasia Theodoropoulou, Anita Nasrallah, Luciano A. Abriata, Laurence Abrami, Juliane Da Graça, Irmak Kaysudu, Francesco Talotta, Maria J. Marcaida, Muhammad U. Anwar, Ondrej Kováč, Sergey Y. Vakhrushev, Alejandro Alonso-Calleja, Sylvia Ho, Antonino Asaro, Francisco S. Mesquita, Leila Alieh, Charlotte Gehin, Lucie Bracq, Nika Goršek, Sarah Vacle, Arthur Samurkas, Alessio Prunotto, Luca Fusar Bassini, Miroslav Machala, Olaia Naveiras, Katrine T. Schjoldager, F. Gisou van der Goot, Matteo Dal Peraro, Giovanni D’Angelo   +28 more
doaj   +2 more sources

The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-κB signaling pathway

Journal of Experimental & Clinical Cancer Research, 2017
Background Chemo-resistance is a leading cause of tumor relapse and treatment failure in patients with ovarian cancer. The identification of effective strategies to overcome drug resistance will have a significant clinical impact on the disease.
Shanyang He, Gang Niu, Jianhong Shang, Yalan Deng, Zhiyong Wan, Cai Zhang, Zeshan You, Hongwei Shen   +7 more
doaj   +2 more sources

Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas [PDF]

Cell Proliferation, 2019
Yu Rutong, Xiuping Zhou
exaly   +2 more sources

The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3. [PDF]

Oncotarget, 2015
The highly conserved Golgi phosphoprotein 3 (GOLPH3) protein, a component of Trans-Golgi Network (TGN), has been defined as a “first-in-class Golgi oncoprotein” and characterized as a Phosphatidylinositol 4-phosphate [PI(4)P] effector at the Golgi ...
Sechi S, Frappaolo A, Belloni G, Colotti G, Giansanti MG.   +4 more
europepmc   +2 more sources