Results 81 to 90 of about 18,240,259 (142)

Center of Golgi cisternae at higher magnification [Secretory pathway; 6f]

, 2011
Presents details of the Golgi matrix and tethered transport vesicles are revealed. Clathrin coated buds are readily apparent on the trans-most cisternae and post-Golgi compartments.
McIntosh, J. Richard, Marsh, Brad J., Howell, Kathryn E.   +2 more
core   +2 more sources

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Chandipura Virus: An Emerging Neurological Threat Transmitted by Sandflies in India

Immunity, Inflammation and Disease, Volume 14, Issue 7, July 2026.
Chandipura virus (CHPV), a neurotropic arbovirus transmitted primarily by sandflies, has emerged as a significant public health concern in India following recurrent outbreaks with high pediatric fatality rates. This review highlights the virus's virology, transmission dynamics, clinical features, and the urgent need for improved diagnostics ...
Abrar Ahmad Zargar, Reena Gupta, P. Krishnamoorthy   +2 more
wiley   +1 more source

Adaptor SKAP-55 binds p21ras activating exchange factor RasGRP1 and negatively regulates the p21ras-ERK pathway in T-Cells [PDF]

, 2008
While the adaptor SKAP-55 mediates LFA-1 adhesion on T-cells, it is not known whether the adaptor regulates other aspects of signaling. SKAP-55 could potentially act as a node to coordinate the modulation of adhesion with downstream signaling.
Lovatt Matt, Christopher E Rudd, Wu, Zhonglin, Schneider, Helga, Rudd Christopher E., Maqueira-Iglesias, Braudel, Matt Lovatt, Schneider Helga, Monika Raab, Valk, Elke, Smith, Xin, Zhonglin Wu, Klaus Strebhardt, Elke Valk, Strebhardt, Klaus, Rudd, Christopher E., Valk Elke, Strebhardt Klaus, Wang Hongyan, Wu Zhonglin, Braudel Maqueira-Iglesias, Maqueira-Iglesias Braudel, Helga Schneider, Xin Smith, Lovatt, Matt, Raab Monika, Raab, Monika, Wang, Hongyan, Smith Xin, Hongyan Wang   +29 more
core   +1 more source

Center of Golgi cisternae at higher magnification [Secretory pathway; 6f]

, 2016
Presents details of the Golgi matrix and tethered transport vesicles are revealed. Clathrin coated buds are readily apparent on the trans-most cisternae and post-Golgi compartments.
Marsh, Brad J., McIntosh, J. Richard, Howell, Kathryn E.   +2 more
core   +2 more sources

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer

Cancer Medicine, 2017
Golgi phosphoprotein 3 (GOLPH3), a newly recognized oncogene, is associated with tumor growth, metastasis, and poor prognosis in several types of cancer.
Jing Sun, Xiaoming Yang, Ru Zhang, Suqing Liu, Xupei Gan, Xiaowei Xi, Zhenbo Zhang, Youji Feng, Yunyan Sun   +8 more
doaj   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Protein kinases (PKs) are enzymes that catalyze phosphorylation of protein substrates involved in a wide variety of biological signalling pathways. This review describes the different families and mechanisms of action and regulation of protein kinases, together with the different classes of fluorescent biosensors that have been engineered and ...
Timothe Abbura, May C. Morris
wiley   +1 more source

Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study [PDF]

, 1988
Herrmann K, Bischof H-J. Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study. The Journal of Comparative Neurology.
Herrmann, Kathrin, Kathrin Herrmann, Hans-Joachim Bischof, Bischof, Hans-Joachim   +3 more
core   +1 more source

Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. [PDF]

, 2013
Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington"s disease.
Toro Ruiz, Daniel del, Egea Guri, Gustavo, Ginés Padrós, Silvia, Kojima, Masami, Canals i Coll, Josep M., Alberch i Vié, Jordi, 1959-   +5 more
core   +1 more source

GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer

Journal of Translational Medicine, 2012
Background Overexpression of GOLPH3 (Golgi phosphoprotein 3, 34 kDa) is associated with the progression of many solid tumor types leading to an unfavorable clinical outcome.
Li Huan, Guo Ling, Chen Shu-Wei, Zhao Xiao-Hui, Zhuang Shi-Min, Wang Li-Ping, Song Li-Bing, Song Ming   +7 more
doaj   +1 more source