Results 71 to 80 of about 115,721 (241)

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

GnRH-induced Ca2+ signaling patterns and gonadotropin secretion in pituitary gonadotrophs. Functional adaptations to both ordinary and extraordinary physiological demands

Frontiers in Endocrinology, 2013
Pituitary gonadotrophs are a small fraction of the anterior pituitary population, yet they synthesize gonadotropins: luteinizing (LH) and follicle stimulating (FSH), essential for gametogenesis and steroidogenesis.
María Luisa eDurán-Pastén, Tatiana eFiordelisio   +1 more
doaj   +1 more source

Long‐term clinical trajectory of microvillus inclusion disease associated with STXBP2‐related familial hemophagocytic lymphohistiocytosis type 5: A case report

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Familial hemophagocytic lymphohistiocytosis type 5 is caused by biallelic pathogenic variants in STXBP2, which encodes syntaxin‐binding protein, a key regulator of vesicle trafficking. In addition to immune dysregulation, patients with familial hemophagocytic lymphohistiocytosis type 5 may present with severe, persistent diarrhea associated ...
Hiroyuki Tanaka, Mariko Sekiguchi, Yuko Kajiho, Tetsuo Ushiku, Jun Fujishiro, Motohiro Kato   +5 more
wiley   +1 more source

Non-functioning pituitary adenomas: indications for pituitary surgery and post-surgical management

, 2019
Non-functioning pituitary adenomas (NFPAs) are associated with impaired well-being, increased comorbidities, and reduced long-term survival. Data on optimal management of NFPAs around surgical treatment are scarce, and postoperative treatment and follow ...
Skoglund, Thomas,, Johannsson, Gudmundur,, Ragnarsson, Oskar,, Olsson, Daniel S,, Buchfelder, Michael, Esposito, Daniela,   +5 more
core   +1 more source

Aromatase cytochrome P450 enzyme expression in human pituitary

, 2008
Aromatase (P450AROM) converts testosterone to estrogen. This conversion could be important in normal physiology and estradiol-induced tumorigenesis in human pituitary.
Erensoy, Nevin, Senel, Berna, Kadioglu, Pinar, Oral, Gökhan, Ozbek, Ugur, Sav, Aydin, Cetin, Gürsel, Sayitoglu, Müge, Gazioglu, Nurperi   +8 more
core   +2 more sources

The Effects of Tachykinin1 Gene Products on Prepubertal Dabry’s Sturgeon (Acipenser dabrynus) Pituitary Hormone Secretion and Gene Expression

Animals
As an ancient and endangered species unique to the Yangtze River in China, the wild population of the Dabry’s sturgeon has become scarce. Due to the long time till the first sexual maturity of Dabry’s sturgeon, the population of artificially bred Dabry’s
Kan Xiao, Hongtao Huang, Xuetao Shi, Tingting Shu, Xu Cheng, Hejun Du, Jing Yang   +6 more
doaj   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

Wildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva, Sebastien Comte, Tamara Keeley, Maquel Brandimarti, Catherine A. Herbert   +4 more
wiley   +1 more source

Changes in Glycosylation of Pituitary Gonadotropins in Polycystic Ovary Syndrome

, 2014
Aim: PCOS has endocrine and metabolic implications leading to a multicausal approach in pathogenesis. We assessed whether PCOS is conditioned by changes in glycosylation of pituitary gonadotropins. Methods: Nested case-control cohort study.
Renata Saucedo Gracía, Hernández-Quijano T, Zárate A, Sandoval A, Marion DH Rosas, Miriam Ruiz Albarrán, Vargas-Girón A, Luis MB Sánchez, Hernández-Valencia M   +8 more
core   +1 more source

Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function [PDF]

, 2019
Purpose: Functional pituitary adenomas (FPAs) lacking a well-defined pseudocapsule can invade the adjacent pituitary gland. In such situations, peel-off resection of the adjacent pituitary gland after selective adenomectomy might lead to complete tumor ...
Takeuchi, Kazuhito, Wakabayashi, Toshihiko, Ishikawa, Takayuki, Kawabata, Teppei, Inoshita, Naoko, Shimoyama, Yoshie, Nagata, Yuichi, Yamamoto, Taiki   +7 more
core   +1 more source