Results 31 to 40 of about 14,284 (259)
Conformational analysis of gossypol and its derivatives by molecular mechanics [PDF]
Conformations and inversion pathways leading to racemization of all the tautomers of gossypol, gossypolone, anhydrogossypol, and a diethylamine Schiff\u27s base of gossypol were investigated with MM3(2000).
Beisel, Chase +3 more
core +3 more sources
Despite the vast amounts of research and remarkable discoveries that have been made in recent decades, cancer remains a leading cause of death and a major public health concern worldwide.
Dilipkumar Pal +4 more
doaj +1 more source
Small molecule and peptide inhibitors of the pro-survival protein Mcl-1 [PDF]
The ability of protein–protein interactions to regulate cellular processes in both beneficial and detrimental ways has made them obvious drug targets.
Beekman, Andrew, Howell, Lesley
core +1 more source
Plant polyphenol gossypol has anticancer activities. This may increase cottonseed value by using gossypol as a health intervention agent. It is necessary to understand its molecular mechanisms before human consumption.
Heping Cao +3 more
doaj +1 more source
The ejaculated semen consists of two major components viz. sperm cells (spermatozoa) and the fluid part obtained after centrifugation called seminal plasma.
P Perumal
core +2 more sources
Synthesis, characterization and antifungal assessment of optically active bis-organotin compounds derived from (S)-BINOL diesters [PDF]
Background: Organotin(IV) derivatives have appeared recently as potential biologically active metallopharmaceuticals exhibiting a variety of therapeutic activities.
Costantino, Andrea Rosana +6 more
core +1 more source
Isolation and characterization of a novel gossypol-degrading bacteria strain Rumen Bacillus Subtilis [PDF]
Objective The aim of the study was to isolate gossypol-degrading bacteria and to assess its potential for gossypol degradation. Methods Rumen liquid was collected from fistulated cows grazing the experimental pasture.
Yunhua Zhang +5 more
doaj +1 more source
Gossypol, a sesquiterpenoid found in cotton seeds, exerts anticancer effects on several tumor entities due to inhibition of DNA synthesis and other mechanisms.
Mascha Mayer +12 more
doaj +1 more source
Autophagy and urothelial carcinoma of the bladder: A review. [PDF]
The incidence of urothelial carcinoma of the urinary bladder (bladder cancer) remains high. While other solid organ malignancies have seen significant improvement in morbidity and mortality, there has been little change in bladder cancer mortality in the
Chandrasekar, Thenappan +1 more
core +2 more sources
Gossypol is a complex plant polyphenol reported to be cytotoxic and anti-inflammatory, but little is known about its effect on gene expression in macrophages.
Heping Cao, Kandan Sethumadhavan
doaj +1 more source

