Results 121 to 130 of about 216,147 (379)

Perturbing General Uncorrelated Networks

open access: yes, 2004
This paper is a direct continuation of an earlier work, where we studied Erd\"os-R\'enyi random graphs perturbed by an interaction Hamiltonian favouring the formation of short cycles. Here, we generalize these results.
A. Krzywicki   +3 more
core   +2 more sources

Gout and NLRP3 Inflammasome Biology

open access: yesArthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout

open access: yesFrontiers in Pharmacology
BackgroundInterleukin-6 (IL-6) is a pleiotropic cytokine, with specific effects depending on the immune microenvironment. Extensive research has confirmed the pathological roles of the IL-6/JAK2/STAT1/3 signaling pathway in inflammation, autoimmunity ...
Zeng Zhang   +27 more
doaj   +1 more source

Moving the Needle: Improving the Care of the Gout Patient

open access: yesRheumatology and Therapy, 2019
Gout is a the most common inflammatory arthritis in the United States. It is a significant cause of morbidity, disability, lost work days, and high healthcare utilization due to intermittent attacks, chronic inflammation, and joint damage.
Jon Golenbiewski, Robert T. Keenan
doaj   +1 more source

Merry Am Webster! [PDF]

open access: yes, 1976
What makes a word interesting? I ask this rhetorically, not inviting specific response. One has only to scan Word Ways articles to realize that some logophiles fancy word length, while others prefer word construction, word sounds, geographical names, and
Pulliam, Tom
core   +1 more source

Gout [PDF]

open access: yesJournal of the Franklin Institute, 1877
n ...
openaire   +1 more source

Efficacy and Safety of Dotinurad Versus Febuxostat for the Treatment of Gout: A Randomized, Multicenter, Double‐Blind, Phase 3 Trial in China

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicenter, randomized, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad ...
Jia Sun   +19 more
wiley   +1 more source

Hyperuricaemia and Gout: A Review

open access: yesSouth African Family Practice, 2010
Gout is a painful, inflammatory disease that affects more men than women. The incidence of gout has increased substantially over the past few decades, as evidenced by information from the Rochester project. Some of the risk factors for the development of
Amy Kopke, Oppel B.W. Greeff
doaj   +1 more source

Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective We aimed to evaluate the influence of contrast‐enhanced dual‐energy computed tomography (CE‐DECT) in detecting and differentiating rheumatic joint diseases of the hand. Methods In this prospective study, patients with suspected arthritis of the hand were investigated consecutively alongside the standard clinical procedure.
Sevtap Tugce Ulas   +9 more
wiley   +1 more source

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