Results 11 to 20 of about 78,942 (265)

Response to allopurinol and febuxostat according to the fractional excretion of urate in men with gout [PDF]

Arthritis Care &Research, Accepted Article.
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche-Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Pérez Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang-Korng Ea, Thomas Bardin, Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche-Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Pérez Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang-Korng Ea, Thomas Bardin   +27 more
openalex   +2 more sources

Impact of Oral Microbiota on Flavor Perception: From Food Processing to In-Mouth Metabolization

Foods, 2021
Flavor perception during food intake is one of the main drivers of food acceptability and consumption. Recent studies have pointed to the oral microbiota as an important factor modulating flavor perception.
Mathieu Schwartz, Francis Canon, Gilles Feron, Fabrice Neiers, Amparo Gamero   +4 more
doaj   +1 more source

Effect of Clinical Typing on Serum Urate Targets of Benzbromarone in Chinese Gout Patients: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionAchieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.
Xiaomei Xue, Xuan Yuan, Lin Han, Xinde Li, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Lingling Cui, Zhen Liu, Wenyan Sun, Can Wang, Fei Yan, Yuwei He, Aichang Ji, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +20 more
doaj   +1 more source

The ongoing role of serum uric acid in blood pressure

Clinical and Experimental Hypertension, 2017
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou, Yangang Wang, Lingling Cui, Ying Chen, Changgui Li, Jinjiao Zhao   +5 more
doaj   +1 more source

MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

Frontiers in Pharmacology, 2021
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang, Quan-Bo Zhang, Dan Zhu, Dan Zhu, Dan Zhu, Fei Dai, Fei Dai, Yu-Qin Huang, Yu-Qin Huang, Jian-Xiong Zheng, Jian-Xiong Zheng, Yi-Ping Tang, Yi-Ping Tang, Zeng-Rong Dong, Zeng-Rong Dong, Xia Liao, Xia Liao, Yu-Feng Qing, Yu-Feng Qing   +18 more
doaj   +1 more source

Identification of a Novel Mutation in a Pseudohypoparathyroidism Family

International Journal of Endocrinology, 2011
Pseudohypoparathyroidism type Ia (PHP Ia) is defined as a series of disorders characterized by multihormone resistance in end-organs and Albright hereditary osteodystrophy (AHO) phenotype.
Zhi-Min Miao, Can Wang, Bin-Bin Wang, Dong-Mei Meng, Dong-Mei Su, Zhi Cheng, Qiao-Lian Wen, Lin Han, Qing Yu, Xu Ma, Chang-Gui Li   +10 more
doaj   +1 more source

The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective Controlled Cohort Study

Frontiers in Medicine, 2022
ObjectiveInterstitial lung disease (ILD) is a common manifestation of connective tissue disease (CTD) that manifests as several subtypes with significant differences in prognosis.
Jiaqi Wang, Jiaqi Wang, Xiao Wang, Xiao Wang, Xiaoyan Qi, Xiaoyan Qi, Zhijian Sun, Zhijian Sun, Tao Zhang, Yi Cui, Qiang Shu, Qiang Shu   +11 more
doaj   +1 more source

Food oral processing in humans: links between physiological parameters, release of flavour stimuli and flavour perception of food

International Journal of Food Studies, 2018
In humans, food oral processing (FOP) is the first step in the digestive process. It prepares the food for swallowing and to undergo the process of digestion.
Gilles Feron, Christian Salles
doaj   +1 more source

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling

Oncogenesis, 2022
Ras-related C3 botulinum toxin substrate 1 (RAC1) overexpressiosn and hyperactivation are correlated with aggressive growth and other malignant characteristics in a wide variety of cancers including hepatocellular carcinoma (HCC). However, the regulatory
Xiaomin Ma, Xiaoxiao Ma, Lihui Zhu, Yunxue Zhao, Mengmeng Chen, Tao Li, Yueke Lin, Dapeng Ma, Caiyu Sun, Lihui Han   +9 more
doaj   +1 more source

IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue

Cell Death Discovery, 2022
White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential regulators ...
Chaoze Li, Mingsheng Zhao, Ming Zhao, Nuo Chen, Yaxin Guo, Yingxin Du, Yi Zhang, Baihui Cao, Bing Zhan, Chun Guo, Yuan Li, Yan Li, Yongyu Shi, Faliang Zhu, Lining Zhang, Qun Wang   +15 more
doaj   +1 more source