Results 21 to 30 of about 64,826 (258)

Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients

Frontiers in Endocrinology, 2021
ObjectiveTo clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.MethodsWe retrospectively analyzed 237 male gout patients who had two sets of body composition and metabolic measurements ...
Zijing Ran, Xiaomei Xue, Lin Han, Lin Han, Lin Han, Robert Terkeltaub, Robert Terkeltaub, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Ting Zhao, Yuwei He, Can Wang, Xinde Li, Zhen Liu, Lingling Cui, Hailong Li, Hailong Li, Aichang Ji, Shuhui Hu, Jie Lu, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +27 more
doaj   +1 more source

Effect of Clinical Typing on Serum Urate Targets of Benzbromarone in Chinese Gout Patients: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionAchieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.
Xiaomei Xue, Xuan Yuan, Lin Han, Xinde Li, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Lingling Cui, Zhen Liu, Wenyan Sun, Can Wang, Fei Yan, Yuwei He, Aichang Ji, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +20 more
doaj   +1 more source

The ongoing role of serum uric acid in blood pressure

Clinical and Experimental Hypertension, 2017
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou, Yangang Wang, Lingling Cui, Ying Chen, Changgui Li, Jinjiao Zhao   +5 more
doaj   +1 more source

MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

Frontiers in Pharmacology, 2021
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang, Quan-Bo Zhang, Dan Zhu, Dan Zhu, Dan Zhu, Fei Dai, Fei Dai, Yu-Qin Huang, Yu-Qin Huang, Jian-Xiong Zheng, Jian-Xiong Zheng, Yi-Ping Tang, Yi-Ping Tang, Zeng-Rong Dong, Zeng-Rong Dong, Xia Liao, Xia Liao, Yu-Feng Qing, Yu-Feng Qing   +18 more
doaj   +1 more source

Identification of a Novel Mutation in a Pseudohypoparathyroidism Family

International Journal of Endocrinology, 2011
Pseudohypoparathyroidism type Ia (PHP Ia) is defined as a series of disorders characterized by multihormone resistance in end-organs and Albright hereditary osteodystrophy (AHO) phenotype.
Zhi-Min Miao, Can Wang, Bin-Bin Wang, Dong-Mei Meng, Dong-Mei Su, Zhi Cheng, Qiao-Lian Wen, Lin Han, Qing Yu, Xu Ma, Chang-Gui Li   +10 more
doaj   +1 more source

Food oral processing in humans: links between physiological parameters, release of flavour stimuli and flavour perception of food

International Journal of Food Studies, 2018
In humans, food oral processing (FOP) is the first step in the digestive process. It prepares the food for swallowing and to undergo the process of digestion.
Gilles Feron, Christian Salles
doaj   +1 more source

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling

Oncogenesis, 2022
Ras-related C3 botulinum toxin substrate 1 (RAC1) overexpressiosn and hyperactivation are correlated with aggressive growth and other malignant characteristics in a wide variety of cancers including hepatocellular carcinoma (HCC). However, the regulatory
Xiaomin Ma, Xiaoxiao Ma, Lihui Zhu, Yunxue Zhao, Mengmeng Chen, Tao Li, Yueke Lin, Dapeng Ma, Caiyu Sun, Lihui Han   +9 more
doaj   +1 more source

The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective Controlled Cohort Study

Frontiers in Medicine, 2022
ObjectiveInterstitial lung disease (ILD) is a common manifestation of connective tissue disease (CTD) that manifests as several subtypes with significant differences in prognosis.
Jiaqi Wang, Jiaqi Wang, Xiao Wang, Xiao Wang, Xiaoyan Qi, Xiaoyan Qi, Zhijian Sun, Zhijian Sun, Tao Zhang, Yi Cui, Qiang Shu, Qiang Shu   +11 more
doaj   +1 more source

Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese

Hereditas, 2019
Background Serum uric acid (SUA), hyperuricemia (HUA) and gout are complex traits with relatively high heritability. This study aims to identify whether a candidate gene, SLC28A2, exerts susceptibility for SUA fluctuation and incidence of HUA and gout in
Zhaowei Zhou, Zhiqiang Li, Can Wang, Xinde Li, Xiaoyu Cheng, Changgui Li, Yongyong Shi   +6 more
doaj   +1 more source

Gout Storm

American Journal of Case Reports, 2021
BACKGROUND Gout is a chronic disease characterized by deposition of monosodium urate crystals, typically manifesting as arthritis. Clinical presentation of gout usually results from activation of local inflammatory response. Despite being one of the oldest diseases in the world, gout pathophysiology is incompletely understood and clinical features are ...
Martins, Danilo, Tonon, Carolina Rodrigues, Pacca, Rafael Lopes, Matchil, Natanye Lemes, Junior, Luiz Antonio Jorge, Queiroz, Dênis Silva, Pereira, Filipe Welson Leal, Silva, Alana Maia, Padovese, Vinicius, De Toledo Moraes, Marcelo Padovani, Da Silva, Daniel Luiz, Nóbrega, Vinicius Cardoso, Curcelli, Emilio Carlos, Okoshi, Marina Politi   +13 more
openaire   +4 more sources