Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients
ObjectiveTo clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.MethodsWe retrospectively analyzed 237 male gout patients who had two sets of body composition and metabolic measurements ...
Zijing Ran +27 more
doaj +1 more source
What makes gouty inflammation so variable? [PDF]
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core +2 more sources
Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie +4 more
core +1 more source
IntroductionAchieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.
Xiaomei Xue +20 more
doaj +1 more source
Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc +12 more
core +2 more sources
The inflammatory process of gout and its treatment. [PDF]
Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals.
Cronstein, Bruce N, Terkeltaub, Robert
core +2 more sources
The ongoing role of serum uric acid in blood pressure
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou +5 more
doaj +1 more source
Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L +4 more
core
Mapping the Structure of Directed Networks: Beyond the "Bow-tie" Diagram [PDF]
We reveal a hierarchical, multilayer organization of finite components -- i.e., tendrils and tubes -- around the giant connected components in directed networks and propose efficient algorithms allowing one to uncover the entire organization of key real ...
Dorogovtsev, S. N. +3 more
core +3 more sources
Effect of Plectranthus Amboinicus Extract on BUN and Creatinine Levels and Cellular Response Proinflammatory Factors TNF-α and IL-1β on Gout Arthritis Patients [PDF]
The purpose of this research was to develop anti-cytokine-based treatment using extract of Plectranthus amboinicus applied to gout arthritis (GA) patients. The research was quasi experimental, with a pretest-posttest randomized control group design.
Martini, S. (Santi) +3 more
core +2 more sources

