Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. [PDF]
Objective To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalizations for gout. Methods Using linked Clinical Practice Research Datalink and NHS Digital Hospital Episode Statistics data, we described the ...
Roddy, Edward
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'It's just a great muddle when it comes to food': a qualitative exploration of patient decision-making around diet and gout. [PDF]
Objective: Our aim was to understand whether, why and how patients choose to modify their diets after developing gout. Methods: We conducted an inductive thematic secondary analysis of qualitative data from 43 interviews and four focus groups with UK ...
Mallen, Hider, Watson, Roddy
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INTRODUCTION: Gout affects about 5% of men and 1% of women, with up to 80% of people experiencing a recurrent attack within 3 years. METHODS AND OUTCOMES:We conducted a systematic review and aimed to answer the following clinical questions: What are the
Underwood, Martin, Underwood, M.
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Population-based study on the epidemiology of gout [PDF]
Pharmacoepidemiology enables researchers to assess the effects of drugs on outcomes, such as diseases, in large study populations. Furthermore, pharmacoepidemiology is gaining importance in the premarketing phase of the drug development process to ...
Bruderer, Saskia Gabriela
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Onset of comorbidities and flare patterns within pre-existing morbidity clusters in people with gout: 5-year primary care cohort study. [PDF]
OBJECTIVE: To investigate the onset of comorbidities and pattern of flares over five years according to baseline comorbidity clusters in people with gout.
Roddy, Edward +6 more
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Primary Care Diagnosis of Gout Compared to a Primary Care Diagnostic Rule for Gout and to Classification Criteria [PDF]
We read with interest the recent study by Dehlin and colleagues1, investigating the validity of a gout diagnosis in primary care. We have also investigated how a primary care diagnosis of gout compares to a primary care diagnostic rule for gout and to ...
WATSON, LORRAINE +2 more
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Latent Class Growth Analysis of Gout Flare Trajectories: A Three-Year Prospective Cohort Study in Primary Care [PDF]
ObjectiveTo investigate the existence of distinct classes of gout flare trajectories and compare their gout-specific, comorbid, and sociodemographic characteristics.MethodsIn a prospective cohort study, adults with gout who were registered with 20 ...
Mallen +5 more
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Gout Activity Score has predictive validity and is sensitive to change: results from the Nottingham Gout Treatment Trial (Phase II) [PDF]
Objectives: To examine the predictive validity of the Gout Activity Score (GAS), its’ correlation with the Gout Impact Scale (GIS), and their sensitivity to change.Methods: Data from a clinical trial in which participants with ≥1 gout flare in the ...
Abhishek, Abhishek +2 more
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The ongoing role of serum uric acid in blood pressure
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou +5 more
doaj +1 more source
Personalized medicine of urate-lowering therapy for gout [PDF]
Gout is a common and complex form of arthritis that is characterised with hyperuricaemia. It is required urate-lowering therapy (ULT) for lifelong management.
Zhang, Youming, Yan, Dewen
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