Results 31 to 40 of about 89,794 (164)

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review

open access: yesPharmaceuticals, 2023
Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi.
Adwoa Dansoa Tabi-Amponsah   +5 more
doaj   +1 more source

A study on the relationship between odor hedonic ratings and individual odor detection threshold

open access: yesScientific Reports, 2022
Odor hedonic perception (pleasant/unpleasant character) is considered as the first and one of the most prominent dimensions in olfaction and is known to depend on several parameters.
Charlotte Bontempi   +2 more
doaj   +1 more source

Circ_0058051 Targeted miR-129-5P Regulates Autophagy-Related Gene ATG7 to Promote the Inflammation of Gout

open access: yesMediators of Inflammation
Gout is a common autoinflammatory disease that clinically manifests as recurrent joint redness, swelling, and pain, but the molecular mechanism of recurrent gouty inflammation remains unclear.
Jianwei Guo   +8 more
doaj   +1 more source

The role of the NLRP3 inflammasome in gout [PDF]

open access: yes, 2011
Sarah R Kingsbury1,2, Philip G Conaghan1,2, Michael F McDermott1,21Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine 2NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Molecular Medicine, University of Leeds,
Conaghan, P   +5 more
core   +1 more source

Factors Influencing the Serum Uric Acid in Gout with Cerebral Infarction

open access: yesMediators of Inflammation, 2021
Background. Although the relationship between gout and cardiovascular has been well demonstrated, there is little information about the difference between gout with cerebrovascular disease and cardiovascular disease.
Yi Li, Hongyi Yang, Yao Tian, Lihua Duan
doaj   +1 more source

Expression Profile and Potential Function of Circular RNAs in Peripheral Blood Mononuclear Cells in Male Patients With Primary Gout

open access: yesFrontiers in Genetics, 2021
Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) with a single-stranded covalently closed-loop structure, and their abnormal expression may participate in the pathogenesis of various human diseases.
Fei Dai   +11 more
doaj   +1 more source

Risk factors for bone erosion in male patients with gout [PDF]

open access: yes精准医学杂志
Objective To investigate the risk factors associated with bone erosion in male patients with gout. Methods A total of 297 male patients with gout who presented for their initial visit to the Gout Clinical Medical Center of the Affiliated Hospital of ...
HUO Fei, AI Xiaobo, REN Wei, HAN Lin, LI Runze
doaj   +1 more source

Gout - epidemiological studies on work outcomes, airborne risk factors and treatment patterns [PDF]

open access: yes, 2022
The overall aim of the thesis was to describe the contemporary epidemiology and use of urate-lowering therapy (ULT) for gout in the Swedish region of Dalarna, to describe the impact of the disease with regard to sickness absenteeism and to explore ...
Sigurdardottir, Valgerdur
core   +1 more source

Effects of adding urinary alkalizer citrate mixture to febuxostat in gout patients with combined-type hyperuricemia and low urine pH: a prospective cohort study

open access: yesArthritis Research & Therapy
Background People with gout and combined-type hyperuricemia, defined as renal urate overload and renal urate under-excretion, have diminished responsiveness to urate-lowering therapy.
Kai Guo   +17 more
doaj   +1 more source

Natural Changbai mineral water reduces obesity risk through regulating metabolism and gut microbiome in a hyperuricemia male mouse model

open access: yesFrontiers in Nutrition
Access to clean and safe drinking water is essential. This study aimed to evaluate the effect of a kind of small molecular natural mineral water, C-cell mineral water on hyperuricemia male mice metabolism condition.
Maichao Li   +26 more
doaj   +1 more source

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