Results 31 to 40 of about 81,484 (272)

Gout - epidemiological studies on work outcomes, airborne risk factors and treatment patterns [PDF]

open access: yes, 2022
The overall aim of the thesis was to describe the contemporary epidemiology and use of urate-lowering therapy (ULT) for gout in the Swedish region of Dalarna, to describe the impact of the disease with regard to sickness absenteeism and to explore ...
Sigurdardottir, Valgerdur
core   +1 more source

Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese

open access: yesHereditas, 2019
Background Serum uric acid (SUA), hyperuricemia (HUA) and gout are complex traits with relatively high heritability. This study aims to identify whether a candidate gene, SLC28A2, exerts susceptibility for SUA fluctuation and incidence of HUA and gout in
Zhaowei Zhou   +6 more
doaj   +1 more source

IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue

open access: yesCell Death Discovery, 2022
White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential regulators ...
Chaoze Li   +15 more
doaj   +1 more source

Gout Storm

open access: yesAmerican Journal of Case Reports, 2021
BACKGROUND Gout is a chronic disease characterized by deposition of monosodium urate crystals, typically manifesting as arthritis. Clinical presentation of gout usually results from activation of local inflammatory response. Despite being one of the oldest diseases in the world, gout pathophysiology is incompletely understood and clinical features are ...
Martins, Danilo   +13 more
openaire   +4 more sources

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review

open access: yesPharmaceuticals, 2023
Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi.
Adwoa Dansoa Tabi-Amponsah   +5 more
doaj   +1 more source

Primary Care Diagnosis of Gout Compared to a Primary Care Diagnostic Rule for Gout and to Classification Criteria

open access: yes, 2019
We read with interest the recent study by Dehlin and colleagues1, investigating the validity of a gout diagnosis in primary care. We have also investigated how a primary care diagnosis of gout compares to a primary care diagnostic rule for gout and to ...
WATSON, LORRAINE   +2 more
core   +1 more source

Understanding and perceptions of gout: an interdisciplinary assessment among patients, physicians and pharmacists in Italy

open access: yesReumatismo, 2020
The objective was to assess knowledge and therapeutic approaches to the management of gout among healthcare professionals and people with/without gout, in Italy.
L. Punzi, G. Medea
doaj   +1 more source

A study on the relationship between odor hedonic ratings and individual odor detection threshold

open access: yesScientific Reports, 2022
Odor hedonic perception (pleasant/unpleasant character) is considered as the first and one of the most prominent dimensions in olfaction and is known to depend on several parameters.
Charlotte Bontempi   +2 more
doaj   +1 more source

Circ_0058051 Targeted miR-129-5P Regulates Autophagy-Related Gene ATG7 to Promote the Inflammation of Gout

open access: yesMediators of Inflammation
Gout is a common autoinflammatory disease that clinically manifests as recurrent joint redness, swelling, and pain, but the molecular mechanism of recurrent gouty inflammation remains unclear.
Jianwei Guo   +8 more
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

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