Results 21 to 30 of about 174,736 (301)

The first metatarsophalangeal joint in gout: a systematic review and meta analysis [PDF]

open access: yes, 2016
Background: The aim of this review was to qualitatively synthesise studies that have investigated characteristics of the first metatarsophalangeal joint (1st MTP) in gout and to undertake a meta-analysis to estimate the average prevalence of acute 1st ...
Dalbeth, N   +3 more
core   +2 more sources

The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective Controlled Cohort Study

open access: yesFrontiers in Medicine, 2022
ObjectiveInterstitial lung disease (ILD) is a common manifestation of connective tissue disease (CTD) that manifests as several subtypes with significant differences in prognosis.
Jiaqi Wang   +11 more
doaj   +1 more source

Food oral processing in humans: links between physiological parameters, release of flavour stimuli and flavour perception of food

open access: yesInternational Journal of Food Studies, 2018
In humans, food oral processing (FOP) is the first step in the digestive process. It prepares the food for swallowing and to undergo the process of digestion.
Gilles Feron, Christian Salles
doaj   +1 more source

The E3 ubiquitin ligase MG53 inhibits hepatocellular carcinoma by targeting RAC1 signaling

open access: yesOncogenesis, 2022
Ras-related C3 botulinum toxin substrate 1 (RAC1) overexpressiosn and hyperactivation are correlated with aggressive growth and other malignant characteristics in a wide variety of cancers including hepatocellular carcinoma (HCC). However, the regulatory
Xiaomin Ma   +9 more
doaj   +1 more source

IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue

open access: yesCell Death Discovery, 2022
White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential regulators ...
Chaoze Li   +15 more
doaj   +1 more source

First validation of the gout activity score against gout impact scale in a primary care based gout cohort [PDF]

open access: yes, 2017
Objectives To validate the gout activity score (GAS) against the gout impact scale in a primary care based gout cohort. Methods This was a single-centre cross-sectional study.
Abhishek, Abhishek   +5 more
core   +2 more sources

Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese

open access: yesHereditas, 2019
Background Serum uric acid (SUA), hyperuricemia (HUA) and gout are complex traits with relatively high heritability. This study aims to identify whether a candidate gene, SLC28A2, exerts susceptibility for SUA fluctuation and incidence of HUA and gout in
Zhaowei Zhou   +6 more
doaj   +1 more source

Provably Good Solutions to the Knapsack Problem via Neural Networks of Bounded Size [PDF]

open access: yes, 2021
The development of a satisfying and rigorous mathematical understanding of the performance of neural networks is a major challenge in artificial intelligence.
Hertrich, Christoph, Skutella, Martin
core   +3 more sources

A study on the relationship between odor hedonic ratings and individual odor detection threshold

open access: yesScientific Reports, 2022
Odor hedonic perception (pleasant/unpleasant character) is considered as the first and one of the most prominent dimensions in olfaction and is known to depend on several parameters.
Charlotte Bontempi   +2 more
doaj   +1 more source

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review

open access: yesPharmaceuticals, 2023
Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi.
Adwoa Dansoa Tabi-Amponsah   +5 more
doaj   +1 more source

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