Results 21 to 30 of about 216,147 (379)

TET2-mutant clonal hematopoiesis and risk of gout

Blood, 2022
Gout is a common inflammatory arthritis defined by NLRP3 inflammasome– and IL1β-dependent innate immune responses to monosodium urate (MSU) crystals. Agrawal et al identified clonal hematopoiesis of indeterminate potential (CHIP) as a risk factor for ...
M. Agrawal, A. Niroula, P. Cunin, M. McConkey, Veronica Kovalcik, P. G. Kim, W. Wong, L. Weeks, A. E. Lin, P. Miller, C. Gibson, A. Sekar, I. Schaefer, D. Neuberg, R. Stone, A. Bick, M. Uddin, G. Griffin, S. Jaiswal, P. Natarajan, P. Nigrovic, Deepak A. Rao, B. Ebert   +22 more
semanticscholar   +1 more source

Gout. Epidemiology of gout [PDF]

Arthritis Research & Therapy, 2010
Gout is the most prevalent form of inflammatory arthropathy. Several studies suggest that its prevalence and incidence have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic
Edward Roddy, Michael C Doherty
openaire   +2 more sources

Gout and Diet: A Comprehensive Review of Mechanisms and Management

Nutrients, 2022
Gout is well known as an inflammatory rheumatic disease presenting with arthritis and abnormal metabolism of uric acid. The recognition of diet-induced systemic metabolic pathways have provided new mechanistic insights and potential interventions on gout
Yingling Zhang, Simin Chen, Man Yuan, Y. Xu, Hongxi Xu   +4 more
semanticscholar   +1 more source

Inflammatory Response to Regulated Cell Death in Gout and Its Functional Implications

Frontiers in Immunology, 2022
Gout, a chronic inflammatory arthritis disease, is characterized by hyperuricemia and caused by interactions between genetic, epigenetic, and metabolic factors.
Jianan Zhao, K-S Wei, Ping Jiang, Cen Chang, Lingxia Xu, Linshuai Xu, Yiming Shi, Shicheng Guo, Yu Xue, D. He   +9 more
semanticscholar   +1 more source

Metagenomic analysis revealed the potential role of gut microbiome in gout

npj Biofilms and Microbiomes, 2021
Emerging evidence indicates an association between gut microbiome and arthritis diseases including gout. However, how and which gut bacteria affect host urate degradation and inflammation in gout remains unclear.
Yong-liang Chu, Silong Sun, Yufen Huang, Qiang Gao, Xuefeng Xie, Peng Wang, Junxia Li, Lifeng Liang, Xiaohong He, Yiqi Jiang, Maojie Wang, Jianhua Yang, Xiumin Chen, Chu Zhou, Yue Zhao, F. Ding, Yi Zhang, Xiaodong Wu, Xue-yuan Bai, Jiaqi Wu, Xiaozhu Wei, Xianghong Chen, Zhen Yue, Xiaodong Fang, Qingchun Huang, Zhang Wang, Runyue Huang   +26 more
semanticscholar   +1 more source

Trend dynamics of gout prevalence among the Chinese population, 1990-2019: A joinpoint and age-period-cohort analysis

Frontiers in Public Health, 2022
Background The burden of gout is increasing worldwide, which places a heavy burden on society and healthcare systems. This study investigates the independent effects of age, period, and cohort on the gout prevalence from 1990 to 2019 in China, compares ...
Bowen Zhu, Yi-mei Wang, Weiran Zhou, Shi Jin, Z. Shen, Han Zhang, Xiaoyan Zhang, Xiaoqiang Ding, Yang Li   +8 more
semanticscholar   +1 more source

Researches on Gout [PDF]

Journal of the Royal Society of Medicine
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William Budd
openalex   +5 more sources

Prevalence and Risk Factors of Hyperuricemia and Gout: A Cross-sectional Survey from 31 Provinces in Mainland China

Journal of Translational Internal Medicine, 2022
Background and Objetives Hyperuricemia (HUA) and gout seriously influence patients’ quality of life. The current study was performed to investigate the prevalence of HUA and gout and the related risk factors in Chinese adults. Methods Data were collected
Jing Song, C. Jin, Z. Shan, W. Teng, Jing Li   +4 more
semanticscholar   +1 more source

Effect of Clinical Typing on Serum Urate Targets of Benzbromarone in Chinese Gout Patients: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionAchieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.
Xiaomei Xue, Xuan Yuan, Lin Han, Xinde Li, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Lingling Cui, Zhen Liu, Wenyan Sun, Can Wang, Fei Yan, Yuwei He, Aichang Ji, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +20 more
doaj   +1 more source

Gouty arthritis of the spine in a renal transplant patient : a clinical case report: an unusual presentation of a common disease [PDF]

, 2015
Axial gout is a well-documented but uncommon manifestation of gout. Its mimicking nature and the impracticality of axial joint aspiration might considerably delay its diagnosis.
Dhaese, Sofie, STRYCKERS, MARIJKE, Terryn, Wim, VAN DER MEERSCH, HANS, Van Laecke, Steven   +4 more
core   +1 more source