Results 21 to 30 of about 78,942 (265)

Gout Remission as a Goal of Urate-Lowering Therapy: A Critical Review

Pharmaceuticals, 2023
Urate-lowering therapies for the management of gout lead to a reduction in serum urate levels, monosodium urate crystal deposition, and the clinical features of gout, including painful and disabling gout flares, chronic gouty arthritis, and tophi.
Adwoa Dansoa Tabi-Amponsah, Sarah Stewart, Graham Hosie, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
doaj   +1 more source

Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese

Hereditas, 2019
Background Serum uric acid (SUA), hyperuricemia (HUA) and gout are complex traits with relatively high heritability. This study aims to identify whether a candidate gene, SLC28A2, exerts susceptibility for SUA fluctuation and incidence of HUA and gout in
Zhaowei Zhou, Zhiqiang Li, Can Wang, Xinde Li, Xiaoyu Cheng, Changgui Li, Yongyong Shi   +6 more
doaj   +1 more source

A study on the relationship between odor hedonic ratings and individual odor detection threshold

Scientific Reports, 2022
Odor hedonic perception (pleasant/unpleasant character) is considered as the first and one of the most prominent dimensions in olfaction and is known to depend on several parameters.
Charlotte Bontempi, Laurence Jacquot, Gérard Brand   +2 more
doaj   +1 more source

Understanding and perceptions of gout: an interdisciplinary assessment among patients, physicians and pharmacists in Italy

Reumatismo, 2020
The objective was to assess knowledge and therapeutic approaches to the management of gout among healthcare professionals and people with/without gout, in Italy.
L. Punzi, G. Medea
doaj   +1 more source

Factors Influencing the Serum Uric Acid in Gout with Cerebral Infarction

Mediators of Inflammation, 2021
Background. Although the relationship between gout and cardiovascular has been well demonstrated, there is little information about the difference between gout with cerebrovascular disease and cardiovascular disease.
Yi Li, Hongyi Yang, Yao Tian, Lihua Duan
doaj   +1 more source

Time Trends and Predictors of Gout Remission Over 6 Years

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

A machine learning-assisted model for renal urate underexcretion with genetic and clinical variables among Chinese men with gout

Arthritis Research & Therapy, 2022
Objectives The objective of this study was to develop and validate a prediction model for renal urate underexcretion (RUE) in male gout patients. Methods Men with gout enrolled from multicenter cohorts in China were analyzed as the development and ...
Mingshu Sun, Wenyan Sun, Xuetong Zhao, Zhiqiang Li, Nicola Dalbeth, Aichang Ji, Yuwei He, Hongzhu Qu, Guangmin Zheng, Lidan Ma, Jiayi Wang, Yongyong Shi, Xiangdong Fang, Haibing Chen, Tony R. Merriman, Changgui Li   +15 more
doaj   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Natural Changbai mineral water reduces obesity risk through regulating metabolism and gut microbiome in a hyperuricemia male mouse model

Frontiers in Nutrition
Access to clean and safe drinking water is essential. This study aimed to evaluate the effect of a kind of small molecular natural mineral water, C-cell mineral water on hyperuricemia male mice metabolism condition.
Maichao Li, Maichao Li, Maichao Li, Kai Guo, Kai Guo, Kai Guo, Yuwei He, Yuwei He, Hailong Li, Wenyan Sun, Wenyan Sun, Wenyan Sun, Xuan Yuan, Xuan Yuan, Xuan Yuan, Zhen Liu, Zhen Liu, Xinde Li, Xinde Li, Tony R. Merriman, Tony R. Merriman, Changgui Li, Changgui Li, Changgui Li, Hui Zhang, Hui Zhang, Hui Zhang   +26 more
doaj   +1 more source

Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulator

Annals of Thoracic Medicine, 2012
The CFTR gene is unique within the ATP-binding cassette (ABC) protein family, predominantly of transporters, by coding a chloride channel. The gating mechanism of ABC proteins has been characterized by the ATP Switch model in terms cycles of dimer ...
Taras Gout
doaj   +1 more source