Results 21 to 30 of about 77,630 (206)

Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study

Arthritis Research & Therapy, 2022
Background Patients with gout frequently have low urinary pH, which is associated with the nephrolithiasis. However, the specific distribution of urinary pH and potential relationship of acidic urine pH to broader manifestations of kidney disease in gout
Yuwei He, Xiaomei Xue, Robert Terkeltaub, Nicola Dalbeth, Tony R. Merriman, David B. Mount, Zhe Feng, Xinde Li, Lingling Cui, Zhen Liu, Yan Xu, Ying Chen, Hailong Li, Aichang Ji, Xiaopeng Ji, Xuefeng Wang, Jie Lu, Changgui Li   +17 more
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Cadmium exposure dysregulates purine metabolism and homeostasis across the gut-liver axis in a mouse model

Ecotoxicology and Environmental Safety, 2023
Cadmium (Cd) exposure has been associated with the development of enterohepatic circulation disorders and hyperuricemia, but the possible contribution of chronic low-dose Cd exposure to disease progression is still need to be explored.
Hui Zhang, Meng Xiu, Hailong Li, Maichao Li, Xiaomei Xue, Yuwei He, Wenyan Sun, Xuan Yuan, Zhen Liu, Xinde Li, Tony R. Merriman, Changgui Li   +11 more
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Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients

Frontiers in Endocrinology, 2021
ObjectiveTo clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.MethodsWe retrospectively analyzed 237 male gout patients who had two sets of body composition and metabolic measurements ...
Zijing Ran, Xiaomei Xue, Lin Han, Lin Han, Lin Han, Robert Terkeltaub, Robert Terkeltaub, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Ting Zhao, Yuwei He, Can Wang, Xinde Li, Zhen Liu, Lingling Cui, Hailong Li, Hailong Li, Aichang Ji, Shuhui Hu, Jie Lu, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +27 more
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Impact of Oral Microbiota on Flavor Perception: From Food Processing to In-Mouth Metabolization

Foods, 2021
Flavor perception during food intake is one of the main drivers of food acceptability and consumption. Recent studies have pointed to the oral microbiota as an important factor modulating flavor perception.
Mathieu Schwartz, Francis Canon, Gilles Feron, Fabrice Neiers, Amparo Gamero   +4 more
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Effect of Clinical Typing on Serum Urate Targets of Benzbromarone in Chinese Gout Patients: A Prospective Cohort Study

Frontiers in Medicine, 2022
IntroductionAchieving a goal of serum urate levels in patients with gout is an important way to prevent gout and its complications while it remains difficult with a low targeting rate worldwidely.
Xiaomei Xue, Xuan Yuan, Lin Han, Xinde Li, Tony R. Merriman, Tony R. Merriman, Tony R. Merriman, Lingling Cui, Zhen Liu, Wenyan Sun, Can Wang, Fei Yan, Yuwei He, Aichang Ji, Jie Lu, Jie Lu, Jie Lu, Changgui Li, Changgui Li, Changgui Li, Changgui Li   +20 more
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The ongoing role of serum uric acid in blood pressure

Clinical and Experimental Hypertension, 2017
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou, Yangang Wang, Lingling Cui, Ying Chen, Changgui Li, Jinjiao Zhao   +5 more
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IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue

Cell Death Discovery, 2022
White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential regulators ...
Chaoze Li, Mingsheng Zhao, Ming Zhao, Nuo Chen, Yaxin Guo, Yingxin Du, Yi Zhang, Baihui Cao, Bing Zhan, Chun Guo, Yuan Li, Yan Li, Yongyu Shi, Faliang Zhu, Lining Zhang, Qun Wang   +15 more
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MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

Frontiers in Pharmacology, 2021
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang, Quan-Bo Zhang, Dan Zhu, Dan Zhu, Dan Zhu, Fei Dai, Fei Dai, Yu-Qin Huang, Yu-Qin Huang, Jian-Xiong Zheng, Jian-Xiong Zheng, Yi-Ping Tang, Yi-Ping Tang, Zeng-Rong Dong, Zeng-Rong Dong, Xia Liao, Xia Liao, Yu-Feng Qing, Yu-Feng Qing   +18 more
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The Efficacy and Safety of Pirfenidone Combined With Immunosuppressant Therapy in Connective Tissue Disease-Associated Interstitial Lung Disease: A 24-Week Prospective Controlled Cohort Study

Frontiers in Medicine, 2022
ObjectiveInterstitial lung disease (ILD) is a common manifestation of connective tissue disease (CTD) that manifests as several subtypes with significant differences in prognosis.
Jiaqi Wang, Jiaqi Wang, Xiao Wang, Xiao Wang, Xiaoyan Qi, Xiaoyan Qi, Zhijian Sun, Zhijian Sun, Tao Zhang, Yi Cui, Qiang Shu, Qiang Shu   +11 more
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Identification of a Novel Mutation in a Pseudohypoparathyroidism Family

International Journal of Endocrinology, 2011
Pseudohypoparathyroidism type Ia (PHP Ia) is defined as a series of disorders characterized by multihormone resistance in end-organs and Albright hereditary osteodystrophy (AHO) phenotype.
Zhi-Min Miao, Can Wang, Bin-Bin Wang, Dong-Mei Meng, Dong-Mei Su, Zhi Cheng, Qiao-Lian Wen, Lin Han, Qing Yu, Xu Ma, Chang-Gui Li   +10 more
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