Results 31 to 40 of about 216,147 (379)

The role of gut microbiota in gout: Is gut microbiota a potential target for gout treatment

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Numerous studies have demonstrated that gut microbiota is essential for the host’s health because it regulates the host’s metabolism, endocrine, and immune systems.
Shuting Tong   +7 more
semanticscholar   +1 more source

YouTube as a source of information on gout: a quality analysis

open access: yesRheumatology International, 2021
YouTube is a popular video-sharing platform commonly visited by patients and healthcare professionals for medical information. Gout is the most frequent cause of inflammatory arthritis in adults.
M. E. Onder, O. Zengin
semanticscholar   +1 more source

What makes gouty inflammation so variable? [PDF]

open access: yes, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core   +2 more sources

Distinct Gut Microbiota in Patients with Asymptomatic Hyperuricemia: A Potential Protector against Gout Development

open access: yesYonsei medical journal, 2022
Purpose Here, we aimed to elucidate the differences in microbiota composition between patients with gout and those with asymptomatic hyperuricemia (asHU) and determine the effect of uric acid-lowering therapy (ULT) on the gut microbiome.
Hye Won Kim   +3 more
semanticscholar   +1 more source

The ongoing role of serum uric acid in blood pressure

open access: yesClinical and Experimental Hypertension, 2017
Positive association between blood pressure (BP) and uric acid is evident, but specific effect size of serum uric acid (SUA) at different levels on BP is unclear, and interaction effect of SUA with other metabolic factors on BP was rarely reported.
Hui Zhou   +5 more
doaj   +1 more source

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]

open access: yes, 2016
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc   +12 more
core   +2 more sources

The biomarkers discovery of hyperuricemia and gout: proteomics and metabolomics

open access: yesPeerJ, 2022
Background Hyperuricemia and gout are a group of disorders of purine metabolism. In recent years, the incidence of hyperuricemia and gout has been increasing, which is a severe threat to people’s health.
Xinghong Wu, Chongge You
semanticscholar   +1 more source

Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization

open access: yesArthritis & Rheumatology, 2021
Hyperuricemia is closely associated with insulin resistance syndrome (and its many cardiometabolic sequelae); however, whether they are causally related has long been debated.
N. McCormick   +6 more
semanticscholar   +1 more source

Provably Good Solutions to the Knapsack Problem via Neural Networks of Bounded Size [PDF]

open access: yes, 2021
The development of a satisfying and rigorous mathematical understanding of the performance of neural networks is a major challenge in artificial intelligence.
Hertrich, Christoph, Skutella, Martin
core   +3 more sources

IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue

open access: yesCell Death Discovery, 2022
White adipose tissue (WAT) homeostasis substantiated by type 2 immunity is indispensable to counteract obesity and metabolic disorders. IL-33/suppression of tumorigenicity (ST) 2 signaling promotes type 2 response in WAT, while potential regulators ...
Chaoze Li   +15 more
doaj   +1 more source

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