Results 51 to 60 of about 157,164 (243)

Musculoskeletal ultrasonography in gout [PDF]

open access: yes, 2015
Gout is a frequent inflammatory disease induced by the deposition of monosodium urate crystals in joints and extra-articular tissues. The natural history of the disease includes four different phases: asymptomatic hyperuricemia, acute attacks ...
Finucci, Annacarla   +3 more
core   +1 more source

Impact of gout on the risk of atrial fibrillation [PDF]

open access: yes, 2016
OBJECTIVES: To examine the risk of atrial fibrillation (AF) at the time of first diagnosis of gout compared with matched controls and to follow incident gout patients and their matched controls after diagnosis to compare their subsequent risk of AF ...
Chang-Fu Kuo   +7 more
core   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Role of ATP binding and hydrolysis in the gating of the cystic fibrosis transmembrane conductance regulator

open access: yesAnnals of Thoracic Medicine, 2012
The CFTR gene is unique within the ATP-binding cassette (ABC) protein family, predominantly of transporters, by coding a chloride channel. The gating mechanism of ABC proteins has been characterized by the ATP Switch model in terms cycles of dimer ...
Taras Gout
doaj   +1 more source

Articulation de deux approches, holiste et analytique, pour étudier le parcours professionnel de l’entrepreneur dirigeant d’entreprise

open access: yesÉducation et Socialisation, 2021
Entrepreneurship is a sought-after research topic and the fields of education and skill training are no exception. However, the latest models of the entrepreneurial process agree on the complexity of this research topic.
Varvara Ciobanu-Gout
doaj   +1 more source

Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]

open access: yes, 2019
Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian   +2 more
core  

Geometric Bremsstrahlung in the Early Universe [PDF]

open access: yes, 1995
We discuss photon emission from particles decelerlated by the cosmic expansion. This can be interpretated as a kind of bremsstrahlung induced by the Universe geometry.
Futamase, T.   +3 more
core   +2 more sources

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

open access: yesAdvanced Science, EarlyView.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu   +7 more
wiley   +1 more source

The Patient Experience of Gout Remission: A Qualitative Study

open access: yesACR Open Rheumatology, 2023
Objective Preliminary remission criteria for gout have been developed. However, the patient experience of gout remission has not been described. This qualitative study aimed to understand the patient experience of gout remission and views about the ...
Adwoa Dansoa Tabi‐Amponsah   +4 more
doaj   +1 more source

Comorbidities in patients with gout prior to and following diagnosis: case-control study [PDF]

open access: yes, 2016
OBJECTIVES: To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis. METHODS: There were 39 111 patients with incident gout and 39 111 matched controls identified from ...
Ab. Usbott   +78 more
core   +2 more sources

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