Results 81 to 90 of about 216,147 (379)

Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities

Nature Reviews Rheumatology, 2021
Gout and chronic kidney disease (CKD) frequently coexist, but quality evidence to guide gout management in people with CKD is lacking. Use of urate-lowering therapy (ULT) in the context of advanced CKD varies greatly, and professional bodies have issued ...
L. Stamp, Hamish Farquhar, H. L. Pisaniello, A. B. Vargas‐Santos, M. Fisher, D. Mount, Hyon K. Choi, R. Terkeltaub, Catherine L. Hill, A. Gaffo   +9 more
semanticscholar   +1 more source

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

Arthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Cost‐effectiveness of low dose colchicine prophylaxis when starting allopurinol using the “start‐low go‐slow” approach for gout: evidence from a non‐inferiority randomised double‐blind placebo‐controlled trial.

Arthritis Care &Research, Accepted Article.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko, Ross Wilson, Nicola Dalbeth, J. Haxby Abbott, Lisa Stamp   +4 more
wiley   +1 more source

DUSP1 Mitigates MSU-Induced Immune Response in Gouty Arthritis Reinforcing Autophagy

Frontiers in Bioscience-Landmark
Background: Persistent hyperuricemia can lead to the generation and deposition of monosodium urate (MSU) crystals. This can trigger gouty arthritis (GA), which in turn induces inflammation.
Jing Nie, Hongbin Qiu
doaj   +1 more source

Musculoskeletal ultrasonography in gout [PDF]

, 2015
Gout is a frequent inflammatory disease induced by the deposition of monosodium urate crystals in joints and extra-articular tissues. The natural history of the disease includes four different phases: asymptomatic hyperuricemia, acute attacks ...
Finucci, Annacarla, Iagnocco, Annamaria, Rutigliano, IOLANDA MARIA, Scirocco, Chiara   +3 more
core   +1 more source

Projected entangled-pair states can describe chiral topological states

, 2013
We show that Projected Entangled-Pair States (PEPS) in two spatial dimensions can describe chiral topological states by explicitly constructing a family of such states with a non-trivial Chern number. They are ground states of two different kinds of free-
Cirac, J. I., Schuch, N., Tu, H. -H., Wahl, T. B.   +3 more
core   +1 more source

Gout in the spine [PDF]

Revista Brasileira de Reumatologia (English Edition), 2013
Axial gout can affect all segments of the spine. It is manifested as back pain, as pain associated with neurological symptoms, and as neurological impairment without pain in 17.9%, 75.8% and 4.2% of cases, respectively. These manifestations were the first presentation of gout in many patients.
Claudia Goldenstein-Schainberg, Eduardo Massato Hasegawa, Ricardo Fuller, Filipe Martins de Mello   +3 more
openaire   +2 more sources

Perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia

Arthritis Care &Research, Accepted Article.
Background/Aims Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia.
Nicola Dalbeth, Sarah Stewart, Gregory D Gamble, Borislav Mihov, Lisa K Stamp, Janine Haslett, William J Taylor, Tony R Merriman, Adwoa Dansoa Tabi‐Amponsah, Anne Horne, Tuhina Neogi, Tristan Pascart, Mariano Andrés, Maria‐Luisa Peral‐Garrido, Eleonora Norkuviene, Janitzia Vazquez Mellado, Till Uhlig, Mingshu Sun, Changgui Li, Keith J Petrie   +19 more
wiley   +1 more source

Approximating the Diameter of Planar Graphs in Near Linear Time [PDF]

, 2013
We present a $(1+\epsilon)$-approximation algorithm running in $O(f(\epsilon)\cdot n \log^4 n)$ time for finding the diameter of an undirected planar graph with non-negative edge ...
Weimann, Oren, Yuster, Raphael
core   +1 more source

A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares

Arthritis & Rheumatology, 2021
To evaluate the efficacy and safety of anakinra compared to triamcinolone in the treatment of gout flares.
K. Saag, P. Khanna, R. Keenan, S. Ohlman, Lisa Osterling Koskinen, E. Sparve, A. Åkerblad, M. Wikén, A. So, M. Pillinger, R. Terkeltaub   +10 more
semanticscholar   +1 more source