Results 81 to 90 of about 139,634 (224)
The Journal of Clinical Pharmacology, EarlyView.Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley +1 more source
Projected entangled-pair states can describe chiral topological states
, 2013 We show that Projected Entangled-Pair States (PEPS) in two spatial dimensions can describe chiral topological states by explicitly constructing a family of such states with a non-trivial Chern number. They are ground states of two different kinds of free-
Cirac, J. I. +3 more
core +1 more source
Longest survivor of pulmonary atresia with ventricular septal defect without surgical intervention
ESC Heart Failure, Volume 12, Issue 2, Page 1499-1507, April 2025.
Sang Zhou +5 more
wiley +1 more source
Gene and Genome Duplication in Spiders
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.In chelicerates whole genome duplications (WGDs) were identified in distinct groups. While there is evidence that Xiphosurans/horseshoe crabs had three rounds of WGD and arachnopulmonates (e.g. spiders and scorpions) had one WGD, in many other arachnid groups no WGD was identified.
Chetan Munegowda +3 more
wiley +1 more source
Molecular mechanisms of Eda‐mediated adaptation to freshwater in threespine stickleback
Molecular Ecology, EarlyView., 2023 Abstract A main goal of evolutionary biology is to understand the genetic basis of adaptive evolution. Although the genes that underlie some adaptive phenotypes are now known, the molecular pathways and regulatory mechanisms mediating the phenotypic effects of those genes often remain a black box.
Carlos E. Rodríguez‐Ramírez +5 more
wiley +1 more source
Journal of Orthopaedic Research, EarlyView.ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan +10 more
wiley +1 more source
Hubungan Tingkat Pengetahuan Tentang Pola Makan Terhadap Sikap Pencegahan Kekambuhan Artritis Gout Di Posyandu Lansia Bagas Waras Kartasura [PDF]
, 2016 Gouty arthritis is the end product of purine metabolism. Uric acid circulating in the human body to be manufactured by the body. Gout patient attitude factor in maintaining the levels of uric acid in her dealing with the prevention of recurrence of gout.
, Arina Maliya S.Kep., Ns.,.M.Si.Med +1 more
core
Giant strongly connected component of directed networks
, 2001 We describe how to calculate the sizes of all giant connected components of a directed graph, including the {\em strongly} connected one. Just to the class of directed networks, in particular, belongs the World Wide Web.
A. Broder +17 more
core +1 more source