Results 11 to 20 of about 9,319 (197)

Gouty Arthritis and Kidneys

open access: yes, 2019
Uric acid is the final product of purine metabolism. Hyperuricemia may result from increased production or reduced excretion of uric acid. Hyperuricemia represents a risk for gouty arthritis.
Ferhan Candan   +5 more
core   +1 more source

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis

open access: yes, 2023
PR domain-containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis.
Nan Xia   +6 more
core   +1 more source

Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis.

open access: yes, 2002
OBJECTIVE: To test the hypothesis that local activation of melanocortin receptor(s) by adrenocorticotropic hormone (ACTH) could be responsible, at least in part, for its efficacy in human gouty arthritis.
Mauro Perretti   +12 more
core   +1 more source

Septic arthritis with concomitant gouty arthritis

open access: yes, 2015
Gouty arthritis is a rare but serious complication of Septic arthritis and presents a diagnostic difficulty. We report a rare case with co-existence of Acute Inflammatory Gouty Arthritis with septic arthritis clinically.
Swaraj F Shelke   +3 more
core   +1 more source

Role of Ultrasonography in Diagnosing Gouty Arthritis

open access: yes, 2011
Urate crystal deposition in the joints is the hallmark of gout. The aim of our study is to determine the characteristic sonographic features of gouty arthritis, and to evaluate the utility of ultrasonography (US) in diagnosing gouty arthritis.
Chiu, Ying-Ming   +3 more
core   +1 more source

Deubiquitinase USP16 induces gouty arthritis via Drp1-dependent mitochondrial fission and NLRP3 inflammasome activation

open access: yes, 2023
Background Gouty arthritis is the most frequently diagnosed inflammatory arthritis worldwide. Dynamin-related protein 1 (Drp1), a regulator of mitochondrial fission, contributes to various inflammatory disorders via activating NLRP3 inflammasome. However,
Qingdong Wang, Hongbin Qiu
core   +1 more source

The pathogenesis of bone erosions in gouty arthritis

open access: yes, 2010
The characteristic radiographic hallmarks of chronic gouty arthritis are the presence of macroscopic tophi and erosions with overhanging edges and relative preservation of the joint space.
Naomi Schlesinger, Ralf G Thiele
core   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

open access: yesArthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch   +6 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

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