Results 21 to 30 of about 9,319 (197)
Pyrazinamide-induced acute gouty arthritis: a case report
, 2022 Gout is a common inflammatory and metabolic disease caused by the deposition of monosodium urate crystals in articular and non-articular tissues. Drugs used to treat tuberculosis, such as pyrazinamide and ethambutol, have been linked to hyperuricaemia ...
Emorinken, Airenakho +1 more
core +1 more source
Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review
Advanced Functional Materials, EarlyView.Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera +6 more
wiley +1 more source
Clostridium butyricum and its metabolites regulate macrophage polarization through miR-146a to antagonize gouty arthritis [PDF]
Journal of Advanced ResearchXianghui Wen
exaly +2 more sources
, 2023 PR domain containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis.
Wang Y. (2884271) +6 more
core +1 more source
Advanced Science, EarlyView.The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang +15 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng +8 more
wiley +1 more source
Peculiarities of gouty arthritis in smokers [PDF]
, 2017 Course of gouty arthritis has clinical and laboratory features, depending on the patient's smoking status. It can be assumed that smoking can reduce the frequency of attacks of gouty arthritis and reduce the concentration of uric acid in the blood ...
Andrusha, Alina +1 more
core
, 2023 Yi Jiang,1,2,* Xin Tu,1,3,* Xia Liao,1,2,* Yixi He,1,2 Shunbing Wang,1,2 Quanbo Zhang,1,3 Yufeng Qing1,2 1Research Center of Hyperuricemia and Gout, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of ...
Jiang Y +6 more
core
Advanced NanoBiomed Research, EarlyView.Platelet membrane‐coated layered double hydroxide nanoparticles were engineered to target inflamed endothelium at early‐stage atherosclerosis and enhance therapeutic efficacy. The biomimetic platform improves stability, immune escape, and inflamed vascular cell targeting, resulting in reduced oxidative stress and downregulated adhesion molecules.
Xiuwen Zhang +4 more
wiley +1 more source
Coexisting ankylosing spondylitis and gouty arthritis
, 2011 Coexsisting ankylosing spondylitis (AS) and gouty arthritis have rarely been reported in the literature previously. We present a 43-year-old male patient with AS who had been diagnosed as having gout based on some clinical and laboratory findings.
Tomruk, Serap Sütbeyaz +2 more
core +1 more source