Results 101 to 110 of about 48,162 (201)

In Silico Identification of Novel Aromatic Compounds as Potential HIV-1 Entry Inhibitors Mimicking Cellular Receptor CD4

open access: yesViruses, 2019
Despite recent progress in the development of novel potent HIV-1 entry/fusion inhibitors, there are currently no licensed antiviral drugs based on inhibiting the critical interactions of the HIV-1 envelope gp120 protein with cellular receptor CD4.
Alexander M. Andrianov   +5 more
doaj   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]

open access: yes, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I.   +10 more
core  

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors

open access: yesCell & Bioscience, 2019
Shaik et al. recently published online the cryo-electron microscopy structure of HIV-1 gp120 in complex with CD4 and CCR5 receptors. This is the first structure of the ternary HIV-1 gp120/CD4/CCR5 complex.
Yongjun Guan
doaj   +1 more source

gp120

open access: yes
Citation: 'gp120' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13164 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Flexible HIV-1 Biosensor Based on the Au/MoS2 Nanoparticles/Au Nanolayer on the PET Substrate

open access: yesNanomaterials, 2019
An electrochemical flexible biosensor composed of gold (Au), molybdenum disulfide nanoparticles (MoS2 NPs), and Au (Au/MoS2/Au nanolayer) on the polyethylene terephthalate (PET) substrate is developed to detect envelope glycoprotein GP120 (gp120), the ...
Minkyu Shin   +4 more
doaj   +1 more source

Neural Circuitry Polarization in the Spinal Dorsal Horn (SDH): A Novel Form of Dysregulated Circuitry Plasticity during Pain Pathogenesis

open access: yesCells
Pathological pain emerges from nociceptive system dysfunction, resulting in heightened pain circuit activity. Various forms of circuitry plasticity, such as central sensitization, synaptic plasticity, homeostatic plasticity, and excitation/inhibition ...
Xufeng Chen, Shao-Jun Tang
doaj   +1 more source

Phospho-Chitooligosaccharides below 1 kDa Inhibit HIV-1 Entry In Vitro

open access: yesCurrent Issues in Molecular Biology
Despite present antiviral agents that can effectively work against HIV-1 replication, side effects and drug resistance have pushed researchers toward novel approaches.
Fatih Karadeniz, Se-Kwon Kim
doaj   +1 more source

Atomic force microscopy fishing and mass spectrometry identification of gp120 on immobilized aptamers

open access: yesInternational Journal of Nanomedicine, 2014
Yuri D Ivanov,1 Natalia S Bukharina,1 Tatyana O Pleshakova,1 Pavel A Frantsuzov,1 Elena Yu Andreeva,1 Anna L Kaysheva,1,2 Victor G Zgoda,1 Alexander A Izotov,1 Tatyana I Pavlova,1 Vadim S Ziborov,1 Sergey P Radko,1 Sergei A Moshkovskii,1 Alexander I ...
Ivanov YD   +12 more
doaj  

Structural and Functional Dysregulation of the Brain Endothelium in HIV Infection and Substance Abuse

open access: yesCells
Blood–brain barrier (BBB) injury and dysfunction following infection with the human immunodeficiency virus (HIV) enables viral entry into the brain, infection of resident brain cells, neuronal injury and subsequent neurodegeneration leading to HIV ...
Narendran Annadurai   +1 more
doaj   +1 more source

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