Results 101 to 110 of about 34,750 (223)
The SPL7013 dendrimer destabilizes the HIV-1 gp120-CD4 complex
, 2015 The poly (l-lysine)-based SPL7013 dendrimer with naphthalene disulphonate surface groups blocks the entry of HIV-1 into target cells and is in clinical trials for development as a topical microbicide.
Nandy, Bidisha +6 more
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Reduction of gp120-induced intracellular ROS production.
, 2013 A) Human mesencephalic neuronal/glial cultures were untreated (C) or pretreated with WIN55,212-2 (0.1 to 1 μM) for 3h followed by gp120 (10 nM) treatment for 72h to measure production of intracellular ROS.
Shuxian Hu (233179) +2 more
core +1 more source
Antibodies elicited by MCPs 419 and 426 partially compete for CD4 binding to gp120.
, 2013 (A) CD4 inhibition of antibodies binding to gp120. (B) MAb 11A8 weakly inhibits CD4 binding to gp120. Reciprocal competition of CD4 and antibodies for binding to gp120 was evaluated by ELISA as described in Materials and Methods with gp120 captured on ...
Hanna C. Kelker (368168) +2 more
core +1 more source
Recognition of native gp120MN and of RCM** gp120MN by antisera elicited by MCPs.
, 2013 *gp120 was denatured as described in the legend of Figure 2.**RCM, reduced, carboxymethylated gp120MN.Sera to 363–384 MCP were harvested after the third boost, and sera to 419–439 MCP or 426–441 MCP after the second boost.
Hanna C. Kelker (368168) +2 more
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Characterization of recombinant HIV-1 gp120-14K fusion proteins.
, 2015 (A) Schematic representation of a codon optimized HIV-1 gp120BX08 fused with VACV A27L gene lacking the first 28 aa. (B) SDS-PAGE of gp120-14K purified proteins under non-reduced condition detected by coomassie staining or western blotting (W.B.) using a
César Santiago (146919) +8 more
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gp120 downregulates Nef dependent IL-6 release.
, 2013 ELISA of IL-6 concentration was measured in pg/ml in immDCs. The first column denotes untreated cells; the second column denotes cells treated with only gp120; the third column denotes cells treated with only Nef; the fourth column denotes cells treated ...
Roni Sarkar (390168) +2 more
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Relative contribution of gp120 and Tat to neurotoxicity.
, 2014 HIV-1-infected MDM supernatants (100 µl) from representative isolates US clade B (HIV-1B:HIV-1ADA), Southern African (HIV-1C:HIV-11084i) and Indian clade C HIV-1 (HIV-1C:HIV-1IndieC1) with equal p24 loads were diluted in SH-SY5Y media and added to SH ...
Eliseo Eugenin (399552) +3 more
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, 2019 Human immunodeficiency virus type-1 (HIV-1) infection is triggered by its envelope (Env) glycoprotein gp120 binding to the host-cell receptor CD4. Although structures of Env/gp120 in the liganded state are known, detailed information about dynamics of ...
Shu-Qun Liu +4 more
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gp120 -binding benzene compounds and saccharide compounds
, 2010 The present invention provides for novel benzene compounds and saccharide compounds and for the use of said compounds for binding, titration (quantification), removing, purifYing or separating the glycoprotein gp120, gp120 comprising viruses or cells ...
San-Félix, Ana +4 more
core
Involvement of cannabinoid receptors in gp120-induced suppression of DA uptake and apoptosis.
, 2013 Human mesencephalic neuronal/glial cultures were untreated (C) or pretreated with SR141716A (CB1 antagonist) or SR144528 (CB2 antagonist) (1 μM) for 30 min prior to WIN55,212-2 (0.3 μM) or JWH015 (CB2 agonist) (1 μM) addition for 3h followed by gp120 (10
Shuxian Hu (233179) +2 more
core +1 more source