Results 181 to 190 of about 48,162 (201)

gp120 neurotoxicity in primary cortical cultures

Advances in Neuroimmunology, 1994
The human immunodeficiency virus type 1 coat protein, gp120, kills neurons in a nitric oxide dependent manner in primary cortical cultures at low picomolar concentrations. gp120 neurotoxicity also requires calcium and glutamate and is blocked by glutamate receptor antagonists.
T M, Dawson, V L, Dawson
openaire   +2 more sources

Synergism Between HIV gp120 and gp120-Specific Antibody in Blocking Human T Cell Activation

Science, 1989
The human immunodeficiency virus (HIV) binds to CD4-positive cells through interaction of its envelope glycoprotein (gp120) with the CD4 molecule. CD4 is a prominent immunoregulatory molecule, and chronic exposure to antibody against CD4 (anti-CD4) has been shown to cause immunodeficiency in mice. T cell-dependent in vitro immune responses
R S, Mittler, M K, Hoffmann
openaire   +2 more sources

Intracellular Signalling Mediating HIV-1 gp120 Neurotoxicity

Cellular Signalling, 1998
During the last few years several studies have been undertaken to characterise the role of gp120, the HIV-1 envelope glycoprotein, in the pathogenesis of neurological defects associated with AIDS. However, neurons did not appear to be the main target of the virus, since the widespread neuronal damage is not associated with a productive viral infection ...
Scorziello A., FLORIO, TULLIO, BAJETTO, ADRIANA, SCHETTINI, GENNARO   +3 more
openaire   +4 more sources

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2019
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openaire   +1 more source

Towards Multispecific Anti‐Gp120 Artificial Antibody

ChemMedChem
Broadly neutralizing antibodies are potential therapeutic drugs that can recognize and block viral entry. But many viruses, such as human immunodeficiency virus (HIV), mutate rapidly and thus evade therapeutic antibodies. Multispecific antibodies and combinations of different antibodies can effectively suppress immune evasion.
Yiwei Sun, Rui Ni, Yuan‐Yuan Liu, Haifang Wang, Aoneng Cao   +4 more
openaire   +2 more sources

Insoluble gp120/anti-gp120 antibody complexes enhance T-cell activation

AIDS, 1993
DELLANNA L, CARBONARI, Maurizio, CIBATI M, AIUTI, Fernando, FIORILLI, Massimo   +4 more
openaire   +3 more sources

gp120 and neurotoxicity in vivo

Trends in Pharmacological Sciences, 1995
S A, Lipton, D E, Brenneman, F S, Silverstein, E, Masliah, L, Mucke   +4 more
openaire   +2 more sources

HIV-1 gp120

2011
Shu-ichi Okamoto, Marcus Kaul, Ian Paul Everall, Eliezer Masliah, Stuart A. Lipton   +4 more
openaire   +1 more source

gp120

2013
openaire   +1 more source

gp120

2008
openaire   +1 more source