Results 111 to 120 of about 61,419 (246)
Asymmetric conformational changes in a GPCR dimer controlled by G-proteins [PDF]
, 2006 Marjorie Damian +4 more
openalex +1 more source
Farnesyl phosphates are endogenous ligands of lysophosphatidic acid receptors: Inhibition of LPA GPCR and activation of PPARs [PDF]
, 2006 Károly Liliom +5 more
openalex +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra +3 more
wiley +1 more source
SNX9 family mediates βarrestin-independent GPCR endocytosis
Communications BiologyAgonist-stimulated GPCR endocytosis typically occurs via the multi-faceted adaptor proteins known as βarrestins. However, endocytosis of several GPCRs occurs independently of β-arrestins, suggesting an additional mode of GPCR endocytosis, but the ...
Valeria L. Robleto +4 more
doaj +1 more source
Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells [PDF]
, 2006 Arun K. Shukla +2 more
openalex +1 more source
Positive Effects of Caffeine Therapy in a Girl with PDE2A‐Related Paroxysmal Dyskinesia
Movement Disorders Clinical Practice, EarlyView.
Katerina Bernardi +2 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Model simplification is a process to simplify large‐scale mathematical models to enable easy applications such as simulation and parameter estimation. A novel heuristic machine analogy method of model simplification was developed and applied to a motivating example of a model for cAMP signaling switch induced by Gi/Gs pathway competition for ...
Liang Yang +3 more
wiley +1 more source
Expression of mammalian GPCRs in C. elegansgenerates novel behavioural responses to human ligands [PDF]
, 2006 Michelle S. Teng +6 more
openalex +1 more source
Recent Advances in Mammalian Olfactory Receptor Function and Structure
Sensory Neuroscience, EarlyView.Olfactory receptors (ORs), a subset of G protein‐coupled receptors (GPCRs), mediate odor detection in sensory neurons and regulate diverse physiological functions across tissues. Their roles in metabolism, immunity, and neural processes underscore their therapeutic relevance. Recent high‐resolution Cryo‐EM studies have unveiled OR activation mechanisms,
Hongxi Qin +9 more
wiley +1 more source