The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120) [PDF]
, 2014 The long-chain fatty acid receptor FFA4(previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease.
Hudson, Brian D. +3 more
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Open Veterinary JournalBackground: In 2021, Vietnam experienced an outbreak of Lumpy skin disease (LSD), which infected 207,687 cattle and buffaloes, as officially reported, and resulted in the culling of 29,182 animals.
Ha Thi Thanh Tran +5 more
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G protein-coupled receptors: the evolution of structural insight
AIMS Biophysics, 2017 G protein-coupled receptors (GPCR) comprise a diverse superfamily of over 800 proteins that have gained relevance as biological targets for pharmaceutical drug design.
Samantha B. Gacasan +2 more
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Erratum: An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology [PDF]
, 2016 Joseph J. Gingell +7 more
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Understanding GPCR dimerization
, 2019 Initially G protein-coupled receptors, GPCRs, were thought to act as monomers, but recently strong evidence has been gathered indicating that they are capable of forming homo- and heterodimers or higher order oligomeric complexes, and that the dimerization phenomenon can modulate the pharmacological response and function of these receptors.
Faron-Górecka, Agata +7 more
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Editorial: Insights in cellular endocrinology: 2022
Frontiers in Endocrinology, 2023 Ralf Jockers, Oreste Gualillo
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Mechanism of Allosteric Communication in GPCR Activation from Microsecond Scale Molecular Dynamics Simulations [PDF]
, 2017 S. Bhattacharya, Nagarajan Vaidehi
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Class-Switching of B Lymphocytes by DNA and Cell Immunization for Stereospecific Monoclonal Antibodies against Native GPCR [PDF]
, 2021 Yushi Isozaki +2 more
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The Application of Artificial Intelligence Accelerates G Protein-Coupled Receptor Ligand Discovery
EngineeringG protein-coupled receptors (GPCRs) are crucial players in various physiological processes, making them attractive candidates for drug discovery. However, traditional approaches to GPCR ligand discovery are time-consuming and resource-intensive.
Wei Chen +4 more
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The Dynamics of Vehicular Networks in Urban Environments [PDF]
, 2010 Vehicular Ad hoc NETworks (VANETs) have emerged as a platform to support intelligent inter-vehicle communication and improve traffic safety and performance.
Dikaiakos, Marios D. +2 more
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