Sub 3Å cryoEM structure using a standard LaB6 120kV TEM upgraded with direct electron detector [PDF]
BIO Web of ConferencesVenugopal Hari +7 more
doaj +1 more source
Sex and sugar in yeast: two distinct GPCR systems
, 2001 Matthias Versele +2 more
openalex +2 more sources
Farnesyl phosphates are endogenous ligands of lysophosphatidic acid receptors: Inhibition of LPA GPCR and activation of PPARs [PDF]
, 2006 Károly Liliom +5 more
openalex +1 more source
Impact of GPCR Structures on Drug Discovery
Cell, 2020 M. Congreve, C. Graaf, N. Swain, C. Tate
semanticscholar +1 more source
Unraveling Novel Genetic Determinants of Thiopurine Response Via TWAS
Clinical Pharmacology &Therapeutics, EarlyView.Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Thiopurines such as 6‐mercaptopurine (6MP) are essential in ALL maintenance therapy. However, dose‐limiting toxicities can significantly disrupt treatment. While genetic variants in TPMT and NUDT15 are known to affect thiopurine response, many patients with normal function ...
Carlotta Bidoli +5 more
wiley +1 more source
Expression of mammalian GPCRs in C. elegansgenerates novel behavioural responses to human ligands [PDF]
, 2006 Michelle S. Teng +6 more
openalex +1 more source
Food Frontiers, EarlyView.Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long +13 more
wiley +1 more source
Genome-wide classification of GPCR sequences using physico-chemical descriptors.
, 2001 Makiko Suwa
openalex +2 more sources
Dimethylsulphoxide as a tool to increase functional expression of heterologously produced GPCRs in mammalian cells [PDF]
, 2006 Arun K. Shukla +2 more
openalex +1 more source
Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies
Food Frontiers, EarlyView.Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue +5 more
wiley +1 more source