Results 181 to 190 of about 92,511 (354)

The GPCR A35 regulates fecundity of <i>Nilaparvata lugens</i> Stål via juvenile hormone signaling. [PDF]

Front Insect Sci
Cao M, Deng D, Mao Z, Duan Z, Sun Y, Zhao X, Ge L.   +6 more
europepmc   +1 more source

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

Science, 2010
Beili Wu, E. Chien, C. Mol, G. Fenalti, Wei Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. Bi, Damon J. Hamel, P. Kuhn, T. Handel, V. Cherezov, R. Stevens   +14 more
semanticscholar   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Author Correction: Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration

Scientific Reports
Chulo Park, Jin‑Woo Lee, Kiheon Kim, Dong‑Seung Seen, Jae‑Yeon Jeong, Won‑Ki Huh   +5 more
doaj   +1 more source

Effect of Ropivacain and Bupivacain on Calcium-Related and G-Protein Coupled Processes in PMNs: A Human In-Vitro Study. [PDF]

Health Sci Rep
Kraus RF, Galla T, Gruber M, Wittmann S.
europepmc   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

Nanobody-drug conjugates for targeting specific GPCR pairs. [PDF]

PLoS Biol
Huang X, Roth BL.
europepmc   +1 more source

MOLECULAR EVOLUTION OF GPCRS: Somatostatin/urotensin II receptors [PDF]

, 2014
Hervé Tostivint, Daniel Ocampo Daza, Christina A Bergqvist, Feng B. Quan, Marion Bougerol, Isabelle Lihrmann, Dan Larhammar   +6 more
openalex   +1 more source

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

Journal of gastroenterology, 2016
Mingming Sun, Wei Wu, Zhanju Liu, Y. Cong   +3 more
semanticscholar   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source