Results 211 to 220 of about 61,419 (246)

Quantitative approaches for studying G protein-coupled receptor signalling and pharmacology.

J Cell Sci
Pearce A, Redfern-Nichols T, Wills E, Rosa M, Manulak I, Sisk C, Huang X, Atakpa-Adaji P, Prole DL, Ladds G.   +9 more
europepmc   +1 more source

Canonical or non-canonical, all aspects of G protein-coupled receptor kinase 2 in heart failure. [PDF]

Acta Physiol (Oxf)
Kaplan A, El-Samadi L, Zahreddine R, Amin G, Booz GW, Zouein FA.   +5 more
europepmc   +1 more source

Cell Biology of Cancer Peritoneal Metastasis: Multiclonal Seeding and Peritoneal Tumor Microenvironment

Cancer Science, EarlyView.
We summarize recent findings on the cell biological aspects of peritoneal metastasis and potential therapeutic target molecules. We focus on the molecular mechanisms underlying cluster/spheroid formation in multiclonal peritoneal metastasis and cancer–stroma interactions within the peritoneal tumor microenvironment. ABSTRACT Peritoneal metastasis, also
Hideki Yamaguchi, Makoto Miyazaki
wiley   +1 more source

Fungal Stress Responses and the Importance of GPCRs. [PDF]

J Fungi (Basel)
Lara-Martínez D, Tristán-Flores FE, Cervantes-Montelongo JA, Silva-Martínez GA.   +3 more
europepmc   +1 more source

Engineering GPCR signaling pathways with RASSLs

, 2008
Bruce R. Conklin, Edward C. Hsiao, Sylvie Claeysen, Aline Dumuis, Supriya Srinivasan, John Forsayeth, Jean-Marc Guettier, Wei-Chun Chang, Ying Pei, Ken D. McCarthy, Robert A. Nissenson, Jürgen Wess, Joël Bockaert, Bryan L. Roth   +13 more
openalex   +2 more sources

Early Origins of Asthma and Allergies: Clues From Studies in China

Clinical &Experimental Allergy, EarlyView.
The environment we live in harbours both risk and protective factors for asthma and allergies. This is particularly relevant in China, where unique environmental and cultural factors shape disease development. The interplay between these environmental factors, airway immunity, and gut microbiome shapes the susceptibility to asthma and allergies ...
Yike Wang, Jing Yang, Xueling Lai, Agnes Sze‐Yin Leung, Yuhan Xing, Gary Wing‐Kin Wong   +5 more
wiley   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

Cell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai, Kun Huang, Wenrui Li, Tianming Wang, Shen Yue, Zhibin Chen, Guangqian Xing, Qinjun Wei, Jun Yao, Xin Cao   +9 more
wiley   +1 more source

Rapid, semi-automated, and inexpensive radioimmunoassay of cAMP: Application in GPCR-mediated adenylate cyclase assays

, 2008
Justin T. Brown, Andrew Kant, Richard B. Mailman   +2 more
openalex   +2 more sources

Oppositely biased glucagon‐like peptide‐1 receptor agonism does not differentially affect lipid metabolism in APOE*3‐Leiden CETP mice

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims [D3,G40,K41.C16 diacid]exendin‐4 (acyl‐ExD3) and [F1,G40,K41.C16 diacid]exendin‐4 (acyl‐ExF1) are oppositely biased glucagon‐like peptide‐1 (GLP‐1) receptor agonists that preferentially promote β‐arrestin recruitment or G protein‐induced signalling, respectively.
Melanie Modder, Alejandra Tomas, Salwa Afkir, Amanda C. M. Pronk, Trea C. M. Streefland, Reshma A. Lalai, Robin van Eenige, Patrick C. N. Rensen, Ben Jones, Sander Kooijman   +9 more
wiley   +1 more source

The Use of Biologics for Targeting GPCRs in Metastatic Cancers. [PDF]

BioTech (Basel)
McBrien C, O'Connell DJ.
europepmc   +1 more source