Results 241 to 250 of about 92,511 (354)

GPCR desensitization: Acute and prolonged phases.

Cellular Signalling, 2018
S. Rajagopal, S. Shenoy
semanticscholar   +1 more source

Sex differences in the physiological response to acute anterior cruciate ligament overuse

The Journal of Physiology, EarlyView.
Abstract figure legend With equivalent in vivo fatigue loading of the anterior cruciate ligament (ACL), females accumulate more tissue damage and mount a slower reparative response than males, when the applied loads between sexes are equivalent. By contrast, males accumulate less tissue damage and mount a robust reparative response that includes ...
Stephen H. Schlecht, Benjamin E. Loflin, Adam R. Carter, Roufael Hanna, Simran Shergill, Edward M. Wojtys   +5 more
wiley   +1 more source

Molecular Characterization and Epidemiology of Lumpy Skin Disease Virus in Bhutan, 2023. [PDF]

Transbound Emerg Dis
Sharma PM, Wangchuk P, Tshering D, La T, Rinchen S, Thapa NK, Settypalli TBK, Dundon WG, Meki IK, Lamien CE.   +9 more
europepmc   +1 more source

Identification and Classification of Fungal GPCR Gene Families [PDF]

Zhiyin Liu, Asaf Salamov, Igor V. Grigoriev   +2 more
openalex   +1 more source

Adenosine and acute low oxygen conditions suppress urinary bladder contractility through the activation of adenosine 2B receptors and large‐conductance calcium‐activated potassium channels

The Journal of Physiology, EarlyView.
Abstract figure legend Detrusor smooth muscle surrounding the urinary bladder produces transient pressure events essential for sensing bladder fullness during the filling phase. We investigated the role of adenosine, a ubiquitous signalling molecule, in regulating bladder smooth muscle function.
Gerald M. Herrera, Jason L. Rengo, Grant W. Hennig, Thomas J. Heppner, Alexandria M. Hepp, Maria Sancho, Saul Huerta de la Cruz, Mark T. Nelson, Nicholas R. Klug   +8 more
wiley   +1 more source

G protein-coupled receptors in prostate cancer: research progress and therapeutic targets. [PDF]

Front Cell Dev Biol
Xiong W, Zhou B, Shi J, Ni D, Xiong Z.
europepmc   +1 more source

Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

Proceedings of the National Academy of Sciences of the United States of America, 2017
T. Cahill, A. Thomsen, Jeffrey Tarrasch, Bianca Plouffe, Anthony H. Nguyen, Fan Yang, Li-Yin Huang, Alem W. Kahsai, D. Bassoni, Bryant J. Gavino, J. Lamerdin, Sarah Triest, A. Shukla, B. Berger, John Little, Albert Antar, Adi Blanc, C. Qu, Xin Chen, Kouki Kawakami, A. Inoue, J. Aoki, J. Steyaert, Jin-peng Sun, M. Bouvier, G. Skiniotis, R. Lefkowitz   +26 more
semanticscholar   +1 more source

Gαs defines the fundamental coupling mechanism of insulin secretion

Journal of Diabetes Investigation, EarlyView.
Jun Shirakawa
wiley   +1 more source

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

G protein-coupled receptors: pivotal hubs in gastric cancer malignancy-from multidimensional crosstalk to precision therapeutics. [PDF]

J Transl Med
Qin R, Fan X, Huang Y, Duan Y, Wang H.
europepmc   +1 more source