Results 301 to 310 of about 83,092 (356)

Conformational biosensors delineate endosomal G protein regulation by GPCRs. [PDF]

Nat Commun
Wysolmerski B, Fisher NM, Dates AN, Inoue A, Blythe EE, von Zastrow M.   +5 more
europepmc   +1 more source

A structurome-wide census of ICL2 folding in class A GPCRs

Hossein Batebi
openalex   +1 more source

BOLD-GPCRs: A Transformer-Powered App for Predicting Ligand Bioactivity and Mutational Effects across Class A GPCRs. [PDF]

J Chem Inf Model
Provasi D, Konovalov K, Riina N, Cullen O, Filizola M.   +4 more
europepmc   +1 more source

Improving AlphaFold2 Performance in Virtual Screens Targeting GPCRs by Enhancing Binding-Site Conformational Sampling. [PDF]

J Chem Inf Model
Mitjavila-Domènech N, Díaz-Holguín A, Hu H, Kahlous NA, Cabeza de Vaca I, Wallner B, Carlsson J.   +6 more
europepmc   +1 more source

<i>In Vitro</i> Evolution of the Adenosine A_2A Receptor Based on an Antagonist Binding Using a Ribosome Display. [PDF]

J Am Chem Soc
Fukasawa G, Matsuoka Y, Tran DP, Nishigaki H, Fukunaga K, Watanabe T, Doura T, Terasaka N, Kagawa A, Murata T, Kitao A, Kiyonaka S, Matsuura T.   +12 more
europepmc   +1 more source

Re-evaluating Gα protein-response element specificity in GPCR signaling. [PDF]

Commun Biol
Saito A, Kise R, Yamaguchi S, Yanagawa M, Inoue A.   +4 more
europepmc   +1 more source

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Production of GPCR and GPCR complexes for structure determination

Current Opinion in Structural Biology, 2013
Since the first high-resolution structure of the beta 2 adrenergic receptor (b2AR) in 2007, we have seen a growing number of G-protein-coupled receptor (GPCR) structures coming to the repertory, providing a significant progress in our understanding of the structural basis of their function.
Maeda Shoji, Schertler Gebhard FX X
openaire   +4 more sources

GPCR dimerisation

Life Sciences, 2003
The concept that GPCRs exist and potentially function as dimers and/or higher oligomers has progressed recently from hypothesis to being widely accepted. A range of techniques has contributed to this understanding, including co-immunoprecipitation and various forms of fluorescence and bioluminescence resonance energy transfer.
Graeme, Milligan, Douglas, Ramsay, Geraldine, Pascal, Juan J, Carrillo   +3 more
openaire   +2 more sources