Results 71 to 80 of about 119,228 (259)

Cancer incidence in Golestan province: Report of an ongoing population-based cancer registry in Iran between 2004 and 2008 [PDF]

, 2012
Background: Golestan Province, at the western end of the Asian esophageal cancer (EC) belt in northeastern Iran, was reported to have one of the highest worldwide rates of EC in the 1970s.
Aarabi, M., Keshtkar, A., Malekzadeh, R., Nouraie, S.M., Roshandel, G., Sadjadi, A., Sedaghat, S.M., Semnani, S.   +7 more
core   +1 more source

GPCRTree: online hierarchical classification of GPCR function [PDF]

, 2008
Background: G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR.
Alex A Freitas, Alex A Freitas, Andrew Secker, Darren R Flower Open Access, David S Moss, David S Moss, Edward Clark, Jon Timmis, Mark Halling-brown, Matthew N Davies   +9 more
core   +4 more sources

What Makes Antibodies Against G Protein-Coupled Receptors so Special? A Novel Concept to Understand Chronic Diseases

Frontiers in Immunology, 2020
Expressions of G protein-coupled receptors (GPCR) on immune and tissue resident cells are the consequence of the cellular environment, which is highly variable.
Gabriela Riemekasten, Gabriela Riemekasten, Gabriela Riemekasten, Gabriela Riemekasten, Frank Petersen, Frank Petersen, Frank Petersen, Harald Heidecke   +7 more
doaj   +1 more source

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

, 2016
No abstract ...
A Neesse, AD Rhim, BC Özdemir, H Laklai, I Barbieri, JJ Lee, JK Mouw, JM Bailey, Michael F Olson, Nicola Rath, P Bailey, SR Hingorani, SR Hingorani, V Sanz-Moreno   +13 more
core   +1 more source

Global Analysis of Predicted G Protein-Coupled Receptor Genes in the Filamentous Fungus, Neurospora crassa. [PDF]

, 2015
G protein-coupled receptors (GPCRs) regulate facets of growth, development, and environmental sensing in eukaryotes, including filamentous fungi. The largest predicted GPCR class in these organisms is the Pth11-related, with members similar to a protein ...
Ahrendt, Steven R, Barsoum, Andrew H, Borkovich, Katherine A, Cabrera, Ilva E, Cao, Jackie, Carrillo, Alexander J, Castillo, Ronald, Chen, Wan-Ching, Davidson, Liza M, Dinkchian, Alex, Guerrero, Nayeli, Kim, Stephanie, Kitada, Sho M, Krystofova, Svetlana, Lai, Taffani H, Li, Liande, Lim, Andrew, Mach, Ashley, Malekyan, Cristin, Michkov, Alexander V, Moua, Toua R, Pacentine, Itallia V, Servin, Jacqueline A, Torres, Carlos Rojas, Yamamoto, Alaina   +24 more
core  

Ligand regulation of the quaternary organization of cell surface M3 muscarinic acetylcholine receptors analyzed by fluorescence resonance energy transfer (FRET) imaging and homogenous time-resolved FRET [PDF]

, 2010
Flp-In T-REx 293 cells expressing a wild type human M muscarinic acetylcholine receptor construct constitutively and able to express a Receptor Activated Solely by Synthetic Ligand (RASSL) form of this receptor on demand maintained response to the ...
Alvarez-Curto, Elisa, Milligan, Graeme, Pediani, John D., Ward, Richard J.   +3 more
core   +2 more sources

Antibodies Against GPCR

Frontiers in Bioscience, 2018
G-protein-coupled receptors (GPCRs) are the largest family of receptors in humans. GPCRs are seven-transmembrane receptors that are activated by the binding of a ligand to the extracellular domain. In addition to the endogenous ligands, auto-antibodies (aab) can also bind to the GPCRs.
Carlotto, Meyer, Harald, Heidecke
openaire   +2 more sources

Molecular dynamics simulation analysis of structural dynamic cross correlation induced by odorant hydrogen-bonding in mouse eugenol ol- factory receptor

Biophysics and Physicobiology
Structural fluctuations and dynamic cross-correlations in the mouse eugenol olfactory receptor (Olfr73) were studied by molecular dynamics (MD) simulation to characterize the dynamic response of the protein upon ligand binding.
Chisato Okamoto, Koji Ando
doaj   +1 more source

Communication over the network of binary switches regulates the activation of A$_{2A}$ adenosine receptor

, 2014
Dynamics and functions of G-protein coupled receptors (GPCRs) are accurately regulated by the type of ligands that bind to the orthosteric or allosteric binding sites.
Choi, Sun, Hyeon, Changbong, Lee, Yoonji
core   +3 more sources

Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements [PDF]

, 2010
Label-free biosensor technology based on dynamic mass redistribution (DMR) of cellular constituents promises to translate GPCR signaling into complex optical 'fingerprints' in real time in living cells.
Blattermann, S, Drewke, C., Gomeza, J., Hennen, S., Janssen, N., Kebig, A., Kostenis, E., Merten, N., Milligan, G., Mohr, K., Mohr-Andra, M., Muller, A., Schmidt, J., Schroder, R., Smith, N.J., Wenzel, J., Zahn, S.   +16 more
core   +1 more source