Results 1 to 10 of about 115,816 (303)
Catalytic Antioxidant Activity of Bis-Aniline-Derived Diselenides as GPx Mimics [PDF]
Molecules, 2021 Herein, we describe a simple and efficient route to access aniline-derived diselenides and evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good yields via ipso-substitution/reduction from the readily available 2 ...
Giancarlo V. Botteselle +11 more
doaj +4 more sources
Translational regulation of GPx-1 and GPx-4 by the mTOR pathway.
PLoS ONE, 2014 Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate.
Emily N Reinke +4 more
doaj +4 more sources
Research progress of glutathione peroxidase family (GPX) in redoxidation
Frontiers in Pharmacology, 2023 Maintaining the balance of a cell’s redox function is key to determining cell fate. In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost ...
Jun Pei +3 more
semanticscholar +4 more sources
Going Forward and Back: The Complex Evolutionary History of the GPx
Biology, 2021 There is large diversity among glutathione peroxidase (GPx) enzymes regarding their function, structure, presence of the highly reactive selenocysteine (SeCys) residue, substrate usage, and reducing agent preference.
Thomaz Stumpf Trenz +5 more
doaj +2 more sources
Clitorea ternatea flower extract induces platelet-derived growth factor (PDGF) and GPx gene overexpression in ultraviolet (UV) B irradiationinduced collagen loss [PDF]
Medicinski Glasnik, 2023 Aim To determine the effect of Clitorea ternatea flower extract (CTFE) in the gel dosage form on the expression of GPx and platelet-derived growth factor (PDGF) in ultraviolet (UV) - B irradiation-induced collagen loss rat model.
Rizka Sofyanti Putri +7 more
doaj +1 more source
Antioxidant Activity of Tempeh Ethanolic Extract on Male Swiss Mouse Brain
Majalah Obat Tradisional, 2023 Tempeh is an Indonesian food made of soybean (Glycine max (L.) Merr.) by fermentation using Rhizopus spp mold. Soybean has a high content of protein, fatty acids, vitamins, and isoflavone glycosides. Isoflavone glycosides are poorly absorbed in the human
Yohanes Dwiatmaka +3 more
doaj +1 more source
Frontiers in Medicine, 2023 Introduction This study aimed to perform an updated systematic review and meta-analysis to evaluate the effectiveness of saffron supplementation on oxidative stress markers [malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status ...
A. Abedi +5 more
semanticscholar +1 more source
Valproic Acid Attenuates Oxidative Damage in Rat Spleen Tissue Induced By Spinal Cord Damage
Turkish Journal of Agriculture: Food Science and Technology, 2022 Events such as oxidative stress caused by spinal cord injury (SCI) are a serious condition because they negatively affect many organs. Alternative treatment options for this type of injury are quite limited.
Mustafa Ulaş
doaj +1 more source
Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis
Cell Death and Disease, 2022 Retinal pigment epithelium (RPE) degeneration plays an important role in a group of retinal disorders such as retinal degeneration (RD) and age-related macular degeneration (AMD). The mechanism of RPE cell death is not yet fully elucidated.
Ming Yang +7 more
semanticscholar +1 more source
Antioxidants, 2021 Oxidative stress and antioxidants play an important role in obesity etiopathology. Genetic variants, including single nucleotide polymorphisms (SNPs) of the antioxidant-related genes, may impact disease risk in several populations. This preliminary study
Amani M T Gusti +4 more
semanticscholar +1 more source