Results 151 to 160 of about 91,455 (273)

Sleep Deprivation Alters T Cell Dynamics: Melatonin as a Restorative Agent

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep is an essential physiological function regulated by circadian rhythm and homeostatic regulation for emotional and physical health. Conversely, sleep deprivation (SD) is associated with weakened immune system function and overall health, which potentially leads to chronic diseases such as heart disease and diabetes.
Hilal Öztürk, Hakan Çalış, Yusuf Metin Gelmez, Günnur Deniz, Abdullah Yılmaz, Mahmut Alp Kılıç, Nermin Yelmen, Zozan Güleken, Devrim Saribal   +8 more
wiley   +1 more source

Effects of Cannabidiol on TAFAZZIN‐Deficient B‐Lymphoblastoid Cells

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Deficiency of the cardiolipin remodeling enzyme TAFAZZIN causes Barth syndrome (BTHS), resulting in cardiolipin loss, monolysocardiolipin (MLCL) accumulation, and electron transport chain (ETC) abnormalities in B‐lymphoblastoid cells. Effects of the non‐psychotropic phytocannabinoid cannabidiol (CBD) were examined on B‐lymphoblastoid cells from ...
John Z. Chan, Antonia N. Berdeklis, Ming Rong Liu, Fasih A. Rahman, Michelle V. Tomczewski, Mackenzie Q. Graham, Musa Musa, Alex D. Cocco, Ken D. Stark, Joe Quadrilatero, Robin E. Duncan   +10 more
wiley   +1 more source

Intermittent Fasting Enhances Genome Integrity and Cytoprotective Pathways via (BHB) β‐Hydroxybutyrate Signaling and Chromatin Remodeling

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Repeated intermittent fasting elevates hippocampal β‐hydroxybutyrate (BHB), remodels HDAC activity and histone acetylation, and drives a metabolic–epigenetic transition from transient chromatin priming after a single fast to a sustained cytoprotective program associated with reduced DNA damage and enhanced genome maintenance.
Hadar Parnas, Joanna Bartman, Tali Rosenberg, Ronit Yosofov, Noa Gabsi, Asaf Marco   +5 more
wiley   +1 more source

Harboring potential of enzymatic antioxidants in sweet potato [<i>Ipomoea batatas</i> (L.) Lam.] nodal cultures under <i>in vitro</i> NaCl-mediated salinity stress conditions. [PDF]

Front Plant Sci
Mishra A, Dasgupta M, Mohanty S, Tripathy P, Krishnappa HG, Singh S, Chauhan VBS, Arutselvan R, Sahoo BB, Sahoo MR.   +9 more
europepmc   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 1955-1967, 15 March 2026.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source

Environmental Stress Shaping Oxidative Responses in the Invasive Crayfish <i>Procambarus clarkii</i> from Lake Trasimeno. [PDF]

Toxics
Caldaroni B, La Porta G, Dörr AJM, Gentile R, Futia S, Ludovisi A, Pallottini M, Selvaggi R, Bruschi F, Elia AC.   +9 more
europepmc   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Neuroprotective effects of pregabalin in experimental spinal cord injury: An investigation of oxidative stress and antioxidant enzymes in blood and neural tissue. [PDF]

Ulus Travma Acil Cerrahi Derg
Güdü BO, Eseoğlu M, Türköz Y, Gül M, Doğan Z.   +4 more
europepmc   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Advanced oxidation protein products and ischemia-modified albumin as prognostic biomarkers of long-term mortality in community-acquired pneumonia: a prospective observational study. [PDF]

Sci Rep
Napiórkowska-Mastalerz M, Wybranowski T, Sikora J, Wszelaki P, Pyskir J, Michalska W, Pilaczyńska-Cemel M, Kruszewski S, Ciastek B.   +8 more
europepmc   +1 more source