Pharmaceuticals, 2023 Several studies revealed that expression levels of glutathione peroxidase 1 (Gpx-1) can be associated with cancer development, mainly through its role in hydroperoxide scavenging by regulating intracellular reactive oxygen species (ROS) levels. Therefore,
Marlena Brzozowa-Zasada +6 more
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Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]
, 2017 Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P. +8 more
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MiR-146b-5p regulates the scavenging effect of GPx-3 on peroxide in papillary thyroid cancer cells
Heliyon, 2023 Background: Glutathione peroxidase (GPx) is an important antioxidant enzyme in thyroid follicular cells. Reduced levels of glutathione peroxidase 3 (GPx-3) expression in papillary thyroid cancer (PTC) are associated with poor prognosis.
Dan Zhang +4 more
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Weak uniqueness and density estimates for sdes with coefficients depending on some path-functionals [PDF]
, 2017 In this paper, we develop a general methodology to prove weak uniqueness for stochastic differential equations with coefficients depending on some path-functionals of the process.
Frikha, Noufel, Li, Libo
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Asian Journal of Medical Sciences, 2016 Background: Normal metabolic functions generate highly reactive compounds called free radicals in the body. Exercise is accompanied by increased oxygen consumption and enhanced Reactive Oxygen Species (ROS)/free radical production in humans.
Ikekpeazu Joy Ebele
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Divers Transformations Leading to New Potent GPx Mimetics
The 1st International Electronic Conference on Catalysis Sciences, 2020 Designing a highly active and selective Se-therapeutic that mimics the activity of the antioxidant enzyme glutathione peroxidase (GPx) still remains a challenge. Since the discovery of ebselen (N-phenyl-1,2-benzisoselenazol-3(2H)-one) and its ability to act as a GPx mimetic, the search for more effective peroxide scavengers has become a “hot topic” in ...
Jacek Ścianowski +3 more
openaire +2 more sources
Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms [PDF]
, 2019 Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable ...
Abessa, D. M. S. +5 more
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The Effect of Eight Weeks of Aerobic Training on MDA, TAC, GPX, and SOD in Heart Tissue of Wistar Rats [PDF]
ورزش و علوم زیست حرکتیIntroduction and Purpose: Cardiovascular disease is one of the main causes of death in the world. The present study aimed to determine the effect of eight weeks of aerobic exercise on the levels of MDA, TAC, GPX, and SOD in the heart tissue of healthy ...
Elaheh Piralaiy +2 more
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FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Enhancement Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression of Macrobrachium Rosenbergii Fed with Aqueous Morinda Citrifolia Leaves Extract-Supplemented Diet [PDF]
, 2018 Morinda citrifolia, known commercially as noni is often used for enhance immunity, these plant rich of phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed with diets containing of aqueous M.
Chang, C. C. (Chin) +2 more
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