Results 211 to 220 of about 29,098 (325)

Recent Advances in Upconversion Nanoparticles for Therapeutics: From Fundamentals to Cutting‐Edge Applications

Electron, EarlyView.
Rare‐earth‐doped upconversion nanoparticles have emerged as anti‐Stokes nanoprobes for advanced phototherapy in biological systems. This review highlights recent advances in their use for therapeutic applications, spanning from fundamental principles to cutting‐edge technologies, and provides insights into their future development for precision ...
Jinghan Zhang, Jiarui Du, Song Jia, Yang Li, Hans Ågren, Paras N. Prasad, Guanying Chen   +6 more
wiley   +1 more source

Depletion of UBAP2L suppresses colorectal cancer cell proliferation and radiotherapy resistance by regulating GPX4. [PDF]

J Cancer Res Clin Oncol
Li Y, Wang X, Zhang X, Zhao S, Lei J, Xu C.   +5 more
europepmc   +1 more source

ACS Chem Biol [PDF]

While opto-genetics has proven to have tremendous value in revealing the functions of the macromolecular machinery in cells, it is not amenable to exploration of small molecules such as phospholipids (PLs).

core  

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Resveratrol attenuated high intensity exercise training-induced inflammation and ferroptosis via Nrf2/FTH1/GPX4 pathway in intestine of mice

, 2023
ZHE XU, XIAONAN SUN, BIN DING, MING ZI, YAN MA   +4 more
openalex   +2 more sources

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway

, 2023
Jin Ding, Baowei Lu, Lumei Liu, Zixuan Zhong, Neng Wang, Bonan Li, Wen S. Sheng, Qinghu He   +7 more
openalex   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

OTUB1 promotes colorectal cancer progression by stabilizing GPX4 and inhibiting ferroptosis. [PDF]

Discov Oncol
Lin G, Lin X, Lin Q, Zhao J.
europepmc   +1 more source

Guanine-rich RNA sequence binding factor 1 regulates neuronal ferroptosis after spinal cord injury in rats via the GPX4 signaling pathway

, 2023
Jin Wang, Jinqi Lu, Yi Zhu, Qun Huang, Qi Gu, Shoujin Tian, Jianfei Ge, Xiaolong Lin, Weiping Sha   +8 more
openalex   +1 more source