Results 211 to 220 of about 40,571 (376)

Knockdown of TOP2A reverses cisplatin resistance in ovarian cancer by inhibiting EMT via ferroptosis mediated by the TP53/GPX4/SLC7A11 axis [PDF]

Xinyue Liu, Junxia Wang, Yang‐Yu Liu, Yan Han, Zhihai Qin, Yu Wang, Shouhong Gao, Xinghua Li, Yuping Suo   +8 more
openalex   +1 more source

Porous Organic Frameworks‐Based Nanomaterials in Colorectal Cancer Therapy: From Drug Delivery to Personalized Nano‐Vaccine

Cancer Nexus, EarlyView.
ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song, Hao Zhang, Yinghui Wang, Chao Luo   +3 more
wiley   +1 more source

Amide backbone chemical shift assignments for human glutathione peroxidase 4 I129S,L130S mutant (GPX4-U46C-I129S-L130S)

Bostock, Mark J., Mourao, Andre S.D., Popowicz, Grzegorz M., Sattler, Michael   +3 more
openalex   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Radio-Adaptive Responses of Mouse Myocardiocytes [PDF]

One of the most significant occupational hazards to an astronaut is the frequent exposure to radiation. Commonly associated with increased risk for cancer related morbidity and mortality, radiation is also known to increase the risk for cardiovascular ...
Seawright, John W., Westby, Christian M.
core   +1 more source

CBX3 confers ferroptosis resistance during blood-borne metastasis. [PDF]

J Hematol Oncol
Wu C, Liu X, Zhao B, Zhao M, Zhang B, Huang G, Cheng Y, Zheng S, Hu J, Guo L, Guo W, Tan J, Hong X.   +12 more
europepmc   +1 more source

Supplementary Figure S1-S7 from BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in <i>BRCA1</i>-Deficient Cancers

Guang Lei, Chao Mao, Amber D. Horbath, Yuelong Yan, Shirong Cai, Jun Yao, Yan Jiang, Mingchuang Sun, Xiaoguang Liu, Jun Cheng, Zhihao Xu, Hyemin Lee, Qidong Li, Zhengze Lu, Li Zhuang, Mei‐Kuang Chen, Anagha Alapati, Timothy A. Yap, Mien‐Chie Hung, M. James You, Helen Piwnica‐Worms, Boyi Gan   +21 more
openalex   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Gpx4 Deletion-Mediated Macrophage Ferroptosis Alleviates Obesity-Associated Insulin Resistance. [PDF]

FASEB J
Wu S, Peng J, Wang X, Gao H, Fang H, Hu S, Wei Q, Dang Y, Tu H, Zhu M, Peng J, Liu Y, Zeng G, Dai X.   +13 more
europepmc   +1 more source

AlphaFold3-predicted model of full-length human Phospholipid hydroperoxide glutathione peroxidase GPX4 (UniProt P36969) containing selenocysteine residue

Luo, Shiqi; Liu, Xinnan; Wang, Xia; liu, Haotian; Ge, Wei
openalex   +1 more source